EP 0550516 A4 19940406 -
Publication
Application
Priority
US 58972290 A 19900928
Abstract (en)
[origin: WO9205799A1] Disclosed herein are methods for inhibiting cell fusion between human T-lymphocytes infected by human immunodeficiency virus (HIV) or free human immunodeficiency virus and uninfected human T-lymphocytes comprising administering inhibitory effective amounts of HIV protein gp120 and CD4-Immunoadhesion and immunogenic composiitions for use in the methods.
IPC 1-7
IPC 8 full level
C07K 16/10 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 16/1063 (2013.01); C07K 16/2812 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [A] US 4908203 A 19900313 - THORNTON GEORGE B [CA]
- [A] EP 0226513 A1 19870624 - PASTEUR INSTITUT [FR]
- [A] WO 8809181 A2 19881201 - TANOX BIOSYSTEMS INC [US], et al
- [A] LINSLEY ET AL: "EFFECTS OF ANTI-GP120 MONOCLONAL ANTIBODIES ON CD4 RECEPTOR BINDING BY THE ENV PROTEIN OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1", JOURNAL OF VIROLOGY, vol. 62, no. 10, 1988, BALTIMORE,USA, pages 3695 - 3702, XP000579292
- [DA] SKINNER ET AL: "NEUTRALIZING ANTIBODIES TO AN IMMUNODOMINANT ENVELOPE SEQUENCE DO NOT PREVENT GP120 BINDING TO CD4", JOURNAL OF VIROLOGY, vol. 62, no. 11, 1988, BALTIMORE,USA, pages 4195 - 4200
- [PX] CELADA ET AL: "ANTIBODY RAISED AGAINST SOUBLE CD4-RGP120 COMPLEX RECOGNIZES THE CD4 MOIETY AND BLOCKS MEMBRANE FUSION WITHOUT INHIBITING CD4-GP120 BINDING", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 172, October 1990 (1990-10-01), NEW YORK,USA, pages 1143 - 1150
- See references of WO 9205799A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9205799 A1 19920416; AU 653366 B2 19940929; AU 8631791 A 19920428; CA 2091253 A1 19920329; EP 0550516 A1 19930714; EP 0550516 A4 19940406
DOCDB simple family (application)
US 9106079 W 19910826; AU 8631791 A 19910826; CA 2091253 A 19910826; EP 91916608 A 19910826