Global Patent Index - EP 0556197 A4

EP 0556197 A4 19940518 - PROLONGING EXPRESSION OF POLYNUCLEOTIDES INTRODUCED INTO A CELL

Title (en)

PROLONGING EXPRESSION OF POLYNUCLEOTIDES INTRODUCED INTO A CELL

Publication

EP 0556197 A4 19940518 (EN)

Application

EP 91917379 A 19910923

Priority

US 58801390 A 19900925

Abstract (en)

[origin: WO9205250A1] The expression of polynucleotide introduced into a cell by means of a targeted complex of the polynucleotide linked to a cell-specific binding agent can be prolonged by stimulating the cell to replicate.

IPC 1-7

C12N 15/87

IPC 8 full level

A01K 67/027 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); C12N 15/09 (2006.01); C12N 15/87 (2006.01)

CPC (source: EP)

A01K 67/0275 (2013.01); A61K 47/645 (2017.07); A61K 47/6807 (2017.07); A61K 48/00 (2013.01); C12N 15/87 (2013.01); A01K 2217/05 (2013.01)

Citation (search report)

  • [X] WU, G.Y. ET AL.: "Receptor-mediated gene delivery and expression in hepatocytes", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 183, no. 1, July 1990 (1990-07-01), pages 147, XP023838350, DOI: doi:10.1016/0014-2999(90)91416-9
  • [PX] GY WU ET AL.: "Targeted gene delivery: persistence of foreign gene expression achieved by pharmacological means", AASLD ABSTRACTS OF PAPERS. HEPATOLOGY, vol. 12, no. 4, 1990, pages 871
  • [PX] JM WILSON ET AL.: "Targeted gene transfer to hepatocytes in vivo: mechanism(s) of persistent gene expression", AASLD ABSTRACTS OF PAPERS. HEPATOLOGY, vol. 14, no. 4, 1990, pages 922
  • [PX] GEORGE Y. WU ET AL.: "Receptor-mediated gene delivery in vivo", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, no. 22, 5 August 1991 (1991-08-05), BALTIMORE, MD US, pages 14338 - 14342
  • [PX] GEORGE Y. WU ET AL.: "Delivery systems for gene therapy", BIOTHERAPY, vol. 3, no. 1, January 1991 (1991-01-01), DORDRECHT NL, pages 87 - 95
  • See references of WO 9205250A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

WO 9205250 A1 19920402; AU 8628291 A 19920415; CA 2092319 A1 19920326; EP 0556197 A1 19930825; EP 0556197 A4 19940518; JP H06503714 A 19940428

DOCDB simple family (application)

US 9106885 W 19910923; AU 8628291 A 19910923; CA 2092319 A 19910923; EP 91917379 A 19910923; JP 51607991 A 19910923