Title (en)

TREATMENT OF AIDS DEMENTIA, MYELOPATHY, PERIPHERAL NEUROPATHY, AND VISION LOSS.

Title (de)

BEHANDLUNG VON AIDS-ASSOZIIERTER DEMENTIA, MYELOPATHIE, PERIPHERER NEUROPATHIE UND SEHVERLUST.

Title (fr)

TRAITEMENT DES DEMENCES, DES MYELOPATHIES, DES NEUROPATHIES PERIPHERIQUES ET DES PERTES DE VISION LIEES AU SIDA.

Publication

EP 0557290 A4 19930714

Application

EP 91916598 A 19910823

Priority

US 57194990 A 19900823

Abstract (en)

[origin: WO9203137A1] A method of reducing damage to neurons in a human patient infected with a human immunodeficiency virus, involving administering to the patient levemopamil, or a physiologically acceptable salt thereof, in a concentration effective to cause reduction in the gp120-responsive rise in free Ca<++> ion concentration in, and subsequent injury of, the neurons of the patient.

IPC 1-7

A61K 31/00; A61K 31/275

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/275 (2006.01); A61K 31/40 (2006.01); A61K 31/44 (2006.01); A61K 31/445 (2006.01); A61K 31/495 (2006.01); A61K 31/55 (2006.01); A61K 45/00 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); A61P 27/02 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01)

CPC (source: EP)

A61K 31/00 (2013.01); A61K 31/275 (2013.01); A61K 31/40 (2013.01); A61K 31/44 (2013.01); A61K 31/445 (2013.01); A61K 31/495 (2013.01); A61K 31/55 (2013.01); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 27/02 (2017.12); A61P 31/12 (2017.12); A61P 31/18 (2017.12)

Citation (search report)

• [X] ARZNEIMITTELFORSCHUNG vol. 40, no. 5, 1990, pages 511 - 514 L.TURSKI 'N-Methyl-D-aspartat-Rezeptorenkomplex'
• See references of WO 9203137A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

WO 9203137 A1 19920305; EP 0557290 A1 19930901; EP 0557290 A4 19930714; JP H06500554 A 19940120

DOCDB simple family (application)

US 9106048 W 19910823; EP 91916598 A 19910823; JP 51533591 A 19910823