EP 0563145 A1 19931006 - CHELATING AGENTS.
Title (en)
CHELATING AGENTS.
Title (de)
CHELATISIERENDE AGENZIEN.
Title (fr)
CHELATEURS.
Publication
Application
Priority
GB 9027922 A 19901221
Abstract (en)
[origin: WO9211232A1] There are provided chelating agents of formula (I) (wherein n is 0 or 1 and at least one R<1> group comprises a group NR<11>R<14> where one of R<11> and R<14> comprises a cyclic lipophilic group) and metal chelates and salts thereof. The chelates with paramagnetic or heavy metal ions are particularly suited for use as hepatobiliary contrast agents.
Abstract (fr)
L'invention concerne des chélateurs de formule (I) dans laquelle n vaut 0 ou 1 et au moins un groupe R1 comprend un groupe NR11R14 dans lequel R11 ou R14 comprend un groupe lipophilique cyclique. L'invention concerne également des chélates métalliques et des sels desdits chélateurs. Les chélates possédant des ions métal de lourd ou paramagnétiques sont particulièrement utiles comme agents de contraste hépatobiliaires.
IPC 1-7
A61K 31/195; A61K 31/285; A61K 49/00; C07C 237/04; C07C 237/06; C07C 237/12; C07D 209/20; C07D 211/58; C07D 213/40; C07D 213/75; C07D 295/13
IPC 8 full level
A61K 31/19 (2006.01); A61K 31/44 (2006.01); A61K 31/4402 (2006.01); A61K 31/4406 (2006.01); A61K 31/4418 (2006.01); A61K 49/00 (2006.01); A61P 39/02 (2006.01); C07C 229/16 (2006.01); C07C 237/04 (2006.01); C07C 237/06 (2006.01); C07C 237/10 (2006.01); C07C 237/12 (2006.01); C07D 209/20 (2006.01); C07D 211/32 (2006.01); C07D 211/40 (2006.01); C07D 211/58 (2006.01); C07D 213/40 (2006.01); C07D 213/75 (2006.01); C07D 295/12 (2006.01); C07D 295/13 (2006.01)
CPC (source: EP)
A61P 39/02 (2017.12); C07C 237/10 (2013.01); C07D 209/20 (2013.01); C07D 211/58 (2013.01); C07D 213/40 (2013.01); C07D 213/75 (2013.01); C07D 295/13 (2013.01); C07C 2602/08 (2017.04)
Citation (search report)
See references of WO 9211232A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9211232 A1 19920709; CA 2098712 A1 19920622; EP 0563145 A1 19931006; GB 9027922 D0 19910213; JP H06504273 A 19940519
DOCDB simple family (application)
EP 9102468 W 19911220; CA 2098712 A 19911220; EP 92901385 A 19911220; GB 9027922 A 19901221; JP 50139591 A 19911220