EP 0565210 A2 19931013 - Vehicles for oral adminstration of pharmaceutically active acide labile substances.
Title (en)
Vehicles for oral adminstration of pharmaceutically active acide labile substances.
Title (de)
Vehikel für die orale Verarbreichung säurelabiler Pharmaka.
Title (fr)
Véhicules pour l'administration orale de substances pharmaceutiques sensibles aux acides.
Publication
Application
Priority
- EP 92107178 A 19870416
- GB 8610573 A 19860430
Abstract (en)
Improvements in the vehicles for oral administration of pharmaceutically active acid labile substances prone to discolouration, containing the acid labile substance where the administration vehicle comprises a core containing said substance together with an alkaline reacting compound or an alkaline salt of said substance optionally mixed with an alkaline reacting compound, adopting the form either of a number of small beads optionally forming a tablet or a tablet as such and comprising a coating made out of one or more inert reacting subcoating layers comprising tablet excipients which are soluble or rapidly disintegrating in water, or polymeric, water soluble, filmforming compounds, optionally containing pH-buffering, alkaline compounds between the alkaline reacting core and an enteric outer coating layer.
IPC 1-7
IPC 8 full level
A61K 31/415 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 9/30 (2006.01); A61K 9/32 (2006.01); A61K 9/50 (2006.01); A61K 9/52 (2006.01); A61K 9/54 (2006.01); A61K 31/433 (2006.01); A61K 31/44 (2006.01)
CPC (source: EP KR US)
A61K 9/2009 (2013.01 - EP US); A61K 9/2886 (2013.01 - EP US); A61K 9/5073 (2013.01 - EP US); A61K 31/415 (2013.01 - EP KR US); A61K 31/44 (2013.01 - EP KR US)
Designated contracting state (EPC)
AT BE CH DE ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
EP 0244380 A2 19871104; EP 0244380 A3 19881019; EP 0244380 B1 19930107; AR 243377 A1 19930831; AT E139692 T1 19960715; AT E186639 T1 19991215; AU 603568 B2 19901122; AU 7192287 A 19871105; CA 1302891 C 19920609; CN 1025151 C 19940629; CN 87103285 A 19871118; CS 268535 B2 19900314; CS 307387 A2 19890613; CY 1860 A 19870416; DD 260222 B5 19980709; DE 244380 T1 19900208; DE 3751851 D1 19960801; DE 3751851 T2 19961031; DE 3783386 D1 19930218; DE 3783386 T2 19930506; DK 169987 B1 19950424; DK 215987 A 19871031; DK 215987 D0 19870428; DZ 1078 A1 20040913; EG 18517 A 19930430; EP 0502556 A1 19920909; EP 0502556 B1 19960626; EP 0565210 A2 19931013; EP 0565210 A3 19950607; EP 0565210 B1 19991117; ES 2010648 A4 19891201; ES 2010648 T3 19940716; ES 2089277 T3 19961001; FI 871914 A0 19870429; FI 871914 A 19871031; FI 91708 B 19940429; FI 91708 C 19940810; GB 2189699 A 19871104; GB 8610573 D0 19860604; GR 3007448 T3 19930730; GR 890300156 T1 19900314; HK 104095 A 19950707; HK 55497 A 19970509; HU 198385 B 19891030; HU T44171 A 19880229; IE 61837 B1 19941130; IE 871106 L 19871030; IS 1918 B 20040315; IS 3222 A7 19871031; JP H0667837 B2 19940831; JP S62258316 A 19871110; KR 870009718 A 19871130; KR 950004886 B1 19950515; MY 102675 A 19920930; NO 174952 B 19940502; NO 174952 C 19940810; NO 871791 D0 19870429; NO 871791 L 19871102; NZ 220097 A 19900426; PH 24440 A 19900625; PL 265417 A1 19880721; PT 84786 A 19870501; PT 84786 B 19891229; SU 1709894 A3 19920130; US 4853230 A 19890801; YU 46421 B 19931020; YU 68087 A 19880831; ZA 872379 B 19871230
DOCDB simple family (application)
EP 87850126 A 19870416; AR 30744887 A 19870430; AT 92107178 T 19870416; AT 93201612 T 19870416; AU 7192287 A 19870423; CA 535903 A 19870429; CN 87103285 A 19870430; CS 307387 A 19870430; CY 186087 A 19870416; DD 30225487 A 19870429; DE 3751851 T 19870416; DE 3783386 T 19870416; DE 87850126 T 19870416; DK 215987 A 19870428; DZ 870070 A 19870428; EG 24487 A 19870427; EP 92107178 A 19870416; EP 93201612 A 19870416; ES 87850126 T 19870416; ES 92107178 T 19870416; FI 871914 A 19870429; GB 8610573 A 19860430; GR 890300156 T 19900314; GR 930400635 T 19930323; HK 104095 A 19950629; HK 55497 A 19970501; HU 194787 A 19870429; IE 110687 A 19870428; IS 3222 A 19870428; JP 10876387 A 19870430; KR 870004133 A 19870429; MY PI19870542 A 19870425; NO 871791 A 19870429; NZ 22009787 A 19870427; PH 35182 A 19870427; PL 26541787 A 19870429; PT 8478687 A 19870429; SU 4202437 A 19870429; US 4049087 A 19870420; YU 68087 A 19870415; ZA 872379 A 19870401