EP 0575539 A1 19931229 - MEANS FOR IN-VITRO DIAGNOSIS OF CONSTITUENTS OF CYTOPLASMIC GRANULES AND BIOLOGICAL APPLICATIONS.
Title (en)
MEANS FOR IN-VITRO DIAGNOSIS OF CONSTITUENTS OF CYTOPLASMIC GRANULES AND BIOLOGICAL APPLICATIONS.
Title (de)
MITTEL FUER DIE IN VITRO DIAGNOSE VON ZYTOPLASMISCHEN KOERNCHENBESTANDTEILEN UND BIOLOGISCHE ANWENDUNGEN.
Title (fr)
MOYENS POUR LE DIAGNOSTIC IN VITRO DE CONSTITUANTS DE GRANULES CYTOPLASMIQUES ET APPLICATIONS BIOLOGIQUES.
Publication
Application
Priority
FR 9103108 A 19910314
Abstract (en)
[origin: WO9216644A1] The invention relates to means for the detection of constituents of cytoplasmic granules secreted by 'helper' T cells or cytotoxic cells in particular for the detection of granzyme or perforine, characterised in that said means are monoclonal antibodies recognizing specifically an epitope of such constituents by giving rise to an immunologic reaction of the antigen-antibody type.
Abstract (fr)
L'invention concerne des moyens pour la détection de constituants de granules cytoplasmiques sécrétés par des cellules T "helper" ou des cellules cytotoxiques en particulier pour la détection de granzyme ou de perforine caractérisés en ce qu'il s'agit d'anticorps monoclonaux reconnaissant spécifiquement un épitope de ces constituants en donnant lieu à une réaction immunologique de type antigène-anticorps.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01); C12N 5/10 (2006.01); C12N 5/20 (2006.01); C12N 9/64 (2006.01); C12N 15/02 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); C07K 16/18 (2013.01); C07K 16/40 (2013.01); C12N 9/6467 (2013.01)
Citation (search report)
See references of WO 9216644A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9216644 A1 19921001; CA 2106193 A1 19920915; EP 0575539 A1 19931229; FR 2673952 A1 19920918; FR 2673952 B1 19950512; JP H06506112 A 19940714
DOCDB simple family (application)
FR 9200240 W 19920316; CA 2106193 A 19920316; EP 92909090 A 19920316; FR 9103108 A 19910314; JP 50858292 A 19920316