EP 0575583 A4 19950215 - BICYCLOPOLYAZAMACROCYCLOCARBOXYLIC ACID COMPLEXES, THEIR CONJUGATES PROCESSES FOR THEIR PREPARATION, AND USE AS RADIOPHARMACEUTICALS.
Title (en)
BICYCLOPOLYAZAMACROCYCLOCARBOXYLIC ACID COMPLEXES, THEIR CONJUGATES PROCESSES FOR THEIR PREPARATION, AND USE AS RADIOPHARMACEUTICALS.
Title (de)
KOMPLEXE VON BICYCLOPOLYAZAMACROCYCLO CARBONSÄUREN IHRE KONJUGATE, VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG ALS RADIOPHARMAZEUTIKA.
Title (fr)
COMPLEXES D'ACIDES BICYCLOPOLYAZAMACROCYCLOCARBOXYLIQUES, LEURS CONJUGUES, LEURS PROCEDES DE PREPARATION ET LEURS UTILISATIONS COMME AGENTS RADIOPHARMACEUTIQUES.
Publication
Application
Priority
US 80539291 A 19911210
Abstract (en)
[origin: WO9312112A1] Complexes of bicyclopolyazamacrocyclocarboxylic acid compounds with a metal ion, e.g. <153>Sm, <177>Lu, <159>Gd, <149>Pm, <140>La, <175>Yb, <166>Ho, <90>Y, <47>Sc, <186>Re, <188>Re, <142>Pr, <99m>Tc, <67>Ga, <68>Ga, <105>Rh, <97>Ru, <111>In, <113m>In or <115m>In ion, are disclosed. The complexes can be covalently attached to a biologically active molecule, e.g. an antibody or antibody fragment, to form conjugates. The complexes and conjugates are useful as radiopharmaceutical agents for therapy and/or diagnostic purposes. Processes to prepare the complex and conjugate are discussed.
IPC 1-7
C07D 471/08; C07D 221/00; C07D 257/00; C07F 5/00; C07F 13/00; C07F 15/00; A61K 49/00; A61K 49/02; A61K 31/435
IPC 8 full level
A61K 51/04 (2006.01); A61K 51/10 (2006.01); C07B 59/00 (2006.01); C07D 471/08 (2006.01); C07D 487/08 (2006.01)
CPC (source: EP KR)
A61K 51/0482 (2013.01 - EP); A61K 51/1093 (2013.01 - EP); C07B 59/004 (2013.01 - EP); C07D 471/08 (2013.01 - EP); C07D 487/08 (2013.01 - EP); C07F 5/00 (2013.01 - KR); A61K 2121/00 (2013.01 - EP); A61K 2123/00 (2013.01 - EP)
Citation (search report)
- No further relevant documents disclosed
- See references of WO 9312112A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9312112 A1 19930624; AU 3275293 A 19930719; CA 2103553 A1 19930611; EP 0575583 A1 19931229; EP 0575583 A4 19950215; FI 933508 A0 19930809; FI 933508 A 19930831; HU 9302308 D0 19931228; IL 104062 A0 19930513; KR 930703331 A 19931129; MX 9207165 A 19930601; ZA 929578 B 19940610
DOCDB simple family (application)
US 9210663 W 19921210; AU 3275293 A 19921210; CA 2103553 A 19921210; EP 93901383 A 19930705; FI 933508 A 19930809; HU 9302308 A 19921210; IL 10406292 A 19921210; KR 930702370 A 19930809; MX 9207165 A 19921210; ZA 929578 A 19921210