EP 0578757 A4 19950830 - CELL SURFACE RECEPTORS HOMOLOGOUS TO COAGULATION FACTORS V AND VIII
Title (en)
CELL SURFACE RECEPTORS HOMOLOGOUS TO COAGULATION FACTORS V AND VIII
Publication
Application
Priority
US 66795791 A 19910312
Abstract (en)
[origin: WO9216558A1] A new class of cellular receptors extensively homologous but not identical to coagulation factors V and VIII is identified. Specific amino acid residue sequences of the receptor are described. Antibody compositions capable of immunoreacting with polypeptides containing the identified amino acid residue sequences and related diagnostic protocols are also described. The receptors are demonstrated to bind coagulation factor Xa which binding is inhibited by monoclonal antibodies to the receptors.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); C07K 1/00 (2006.01); C07K 14/435 (2006.01); C07K 14/575 (2006.01); C07K 14/705 (2006.01); C07K 14/745 (2006.01); C07K 14/755 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
C07K 14/575 (2013.01); C07K 14/705 (2013.01); C07K 14/745 (2013.01); C07K 16/28 (2013.01)
Citation (search report)
- [A] MCGEE M.P. ET AL.;: "Assembly of the prothrombin activator complex on rabbit alveolar macrophage high-affinity factor Xa receptors", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 164, no. 6, 1 December 1986 (1986-12-01), ROCKEFELLER UNIVERSITY PRESS, US, pages 1902 - 1914
- See references of WO 9216558A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9216558 A1 19921001; AU 1788592 A 19921021; AU 664994 B2 19951214; CA 2105993 A1 19920913; EP 0578757 A1 19940119; EP 0578757 A4 19950830; IE 920765 A1 19920923; JP H06506696 A 19940728; PT 100235 A 19930730; PT 100235 B 19990630
DOCDB simple family (application)
US 9202109 W 19920312; AU 1788592 A 19920312; CA 2105993 A 19920312; EP 92910343 A 19920312; IE 920765 A 19920309; JP 51059792 A 19920312; PT 10023592 A 19920312