EP 0580758 A4 19950405 - ANTI-HUMAN IMMUNODEFICIENCY VIRUS RECOMBINANT ANTIBODIES.
Title (en)
ANTI-HUMAN IMMUNODEFICIENCY VIRUS RECOMBINANT ANTIBODIES.
Title (de)
REKOMBINANTE ANTIKÖRPER GEGEN MENSCHLICHEN IMMUNSCHWÄCHEVIRUS.
Title (fr)
ANTICORPS RECOMBINES ANTI-VIH.
Publication
Application
Priority
US 68737691 A 19910418
Abstract (en)
[origin: WO9218540A1] This invention provides hybrid antibodies which comprise a base portion which corresponds to the constant portion of human immunoglobulin G, a combining site selected for specificity to the particular target antigen, and a combining site which binds to and activates human CTL.
IPC 1-7
IPC 8 full level
C07K 14/705 (2006.01); C07K 14/00 (2006.01); C07K 14/11 (2006.01); C07K 16/00 (2006.01); C07K 16/10 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); G01N 33/531 (2006.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
C07K 14/005 (2013.01); C07K 16/1063 (2013.01); C07K 16/2809 (2013.01); C07K 19/00 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2319/00 (2013.01); C12N 2760/16022 (2013.01)
Citation (search report)
- [X] H. ZAQHOUANI ET AL.: "Recombinant immunoglobulin gene encoding a viral CTL epitope mediates cell killing by specific cytotoxic T lymphocytes.", THE FASEB JOURNAL, vol. 5, no. 5, 15 March 1991 (1991-03-15), BETHESDA MD, USA, pages A1334
- [A] M. SOLLAZZO ET AL.: "Expression of an exogenous peptide epitope genetically engineered in the variable domain of an immunoglobulin: implications for antibody and peptide folding.", PROTEIN ENGINEERING, vol. 4, no. 2, December 1990 (1990-12-01), OXFORD, GB, pages 215 - 220
- [A] P. PEREZ ET AL.: "Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody.", NATURE, vol. 316, 25 July 1985 (1985-07-25), LONDON, GB, pages 354 - 356
- [PX] H. KUZU ET AL.: "In vivo priming of NP-specific CTL with self immunoglobulin bearing an influenza virus epitope.", THE FASEB JOURNAL, vol. 6, no. 5, 28 February 1992 (1992-02-28), BETHESDA MD, USA, pages A1968
- See also references of WO 9218540A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9218540 A1 19921029; AU 1891992 A 19921117; AU 672580 B2 19961010; CA 2107329 A1 19921019; CA 2107329 C 19990427; EP 0580758 A1 19940202; EP 0580758 A4 19950405; IL 101602 A0 19921230; IL 101602 A 19961031; JP H06506947 A 19940804
DOCDB simple family (application)
US 9202975 W 19920410; AU 1891992 A 19920410; CA 2107329 A 19920410; EP 92911196 A 19920410; IL 10160292 A 19920416; JP 51087992 A 19920410