EP 0584264 A1 19940302 - D-TYPE CYCLIN AND USES RELATED THERETO.
Title (en)
D-TYPE CYCLIN AND USES RELATED THERETO.
Title (de)
D-TYP CYCLIN UND DARAUF BEZOGENE ANWENDUNGEN.
Title (fr)
CYCLINES DU TYPE D ET LEURS UTILISATIONS.
Publication
Application
Priority
US 70151491 A 19910516
Abstract (en)
[origin: WO9220796A2] A novel class of cyclins, referred to as D-type cyclins, of mammalian origin, particularly human origin, DNA and RNA encoding the novel cyclins, and a method of identifying other D-type and non-D-type cyclins. Also disclosed are a method of detecting an increased level of a D-type cyclin and a method of inhibiting cell division by interfering with formation of the protein kinase-D-type cyclin complex essential for cell cycle start.
Abstract (fr)
Nouvelle classe de cyclines, appelées cyclines du type D, d'origine mammifère, et notamment d'origine humaine, ADN et ARN codant pour ces nouvelles cyclines, et procédé d'identification d'autres cyclines du type D et du type non D. L'invention se rapporte également à un procédé de détection d'un niveau accru d'une cycline de type D et à une méthode d'inhibition de division cellulaire en empêchant la formation du complexe protéine kinase - cycline du type D essentiel au démarrage du cycle cellulaire.
IPC 1-7
C12N 15/12; C12Q 1/68; C07K 13/00; C07K 15/00; C12P 21/08; G01N 33/53; G01N 33/58
IPC 8 full level
A61K 45/00 (2006.01); A61P 43/00 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01); C12Q 1/48 (2006.01); C12Q 1/68 (2006.01); C12R 1/645 (2006.01)
CPC (source: EP)
A61P 43/00 (2017.12); C07K 14/4738 (2013.01); C07K 16/18 (2013.01)
Citation (search report)
See references of WO 9220796A2
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9220796 A2 19921126; WO 9220796 A3 19930304; CA 2103161 A1 19921117; EP 0584264 A1 19940302; JP 2001299368 A 20011030; JP H06507787 A 19940908
DOCDB simple family (application)
US 9204146 W 19920518; CA 2103161 A 19920518; EP 92913100 A 19920518; JP 2001060722 A 20010305; JP 50024293 A 19920518