EP 0585296 A1 19940309 - 2-(PYRROLIDINYL-1-METHYL)-PIPERIDINE DERIVATIVES AND THEIR USE AS KAPPA-RECEPT OR AGONISTS.

Title (en)

2-(PYRROLIDINYL-1-METHYL)-PIPERIDINE DERIVATIVES AND THEIR USE AS KAPPA-RECEPT OR AGONISTS.

Title (de)

2-(PYRROLIDINYL-1-METHYL)-PIPERIDINDERIVATE UND IHRE VERWENDUNG ALS KAPPA-REZEPTOR-AGONISTEN.

Title (fr)

DERIVES DE 2-(PYRROLIDINYLE-1-METHYLE)-PIPERIDINE ET LEUR UTILISATION COMME AGONISTES DE RECEPTEURS KAPPA.

Publication

EP 0585296 A1 19940309 (EN)

Application

EP 92910424 A 19920515

Priority

GB 9110951 A 19910521
GB 9114772 A 19910709

Abstract (en)

[origin: WO9220657A1] Azacyclic derivatives of formula (I), are kappa-receptor agonists and are useful in the treatment of convulsions, cough, asthma, inflammation, pancreatitis, arrhythmias, hyponatraemic disease states and cerebral ischaemia.

Abstract (fr)

Des dérivés azacycliques ayant la formule (I) sont des agonistes de récepteurs-kappa et peuvent être utilisés pour le traitement des convulsions, de la toux, de l'asthme, des inflammations, de la pancréatite, des arythmies, des états hyponatrémiques et de l'ischémie cérébrale.

IPC 1-7

C07D 211/26; C07D 401/06

IPC 8 full level

A61K 31/445 (2006.01); A61K 31/4427 (2006.01); A61P 7/10 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); A61P 11/00 (2006.01); A61P 25/02 (2006.01); A61P 25/08 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); C07D 401/06 (2006.01)

CPC (source: EP)

A61P 7/10 (2017.12); A61P 9/06 (2017.12); A61P 9/10 (2017.12); A61P 11/00 (2017.12); A61P 25/02 (2017.12); A61P 25/08 (2017.12); A61P 25/28 (2017.12); A61P 29/00 (2017.12); C07D 401/06 (2013.01)

Citation (search report)

See references of WO 9220657A1

Designated contracting state (EPC)

BE CH DE FR GB IT LI NL

DOCDB simple family (publication)

WO 9220657 A1 19921126; AU 1760992 A 19921230; EP 0585296 A1 19940309; IE 921620 A1 19921202; JP H06511231 A 19941215; MX 9202352 A 19921101; PT 100499 A 19940531

DOCDB simple family (application)

EP 9201111 W 19920515; AU 1760992 A 19920515; EP 92910424 A 19920515; IE 921620 A 19920701; JP 51041592 A 19920515; MX 9202352 A 19920519; PT 10049992 A 19920519