EP 0586687 A1 19940316 - TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF.
Title (en)
TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF.
Title (de)
TRANS-SIALIDASE UND METHODEN DER VERWENDUNG UND HERSTELLUNG.
Title (fr)
TRANS-SIALIDASE ET SES PROCEDES D'UTILISATION ET DE FABRICATION.
Publication
Application
Priority
- US 85751992 A 19920325
- US 97385192 A 19921110
Abstract (en)
[origin: WO9318787A1] Polypeptides are provided having trans-sialidase enzymatic activity in substantially pure form, nucleic acids coding therefor, antibodies specific for such polypeptides, processes for producing the enzyme and methods of use of the enzyme, in particular for the synthesis of sialyl alpha (2->3)-linked saccharides, glycoproteins and glycolipids. Such enzymes are isolatable as nucleic acid or amino acid sequences from parasites of the genus Trypanosoma.
Abstract (fr)
L'invention concerne des polypeptides ayant l'activité enzymatique d'une trans-sialidase sous leur forme pratiquement pure, les acides nucléiques les codant, les anticorps spécifiques de ces polypeptides, ainsi que les procédés de production et d'utilisation de ladite enzyme, en particulier pour la synthèse de saccharides à liaison sialyle alpha(2->3), de glycoprotéines et de glycolipides. Ces enzymes peuvent être isolées en tant que séquences d'acides nucléiques ou séquences d'acides aminés à partir de parasites du genre Tripanosoma.
IPC 1-7
A61K 37/52; A61K 39/005; A61K 39/395; C07H 21/02; C07H 21/04; C07K 3/18; C07K 13/00; C12N 5/10; C12N 9/10; C12N 15/30; C12Q 1/48
IPC 8 full level
C07H 3/06 (2006.01); C07H 13/04 (2006.01); C07H 15/04 (2006.01); C07H 15/10 (2006.01); C07K 16/12 (2006.01); C07K 16/20 (2006.01); C07K 16/40 (2006.01); C12N 9/10 (2006.01); C12N 15/30 (2006.01); C12P 19/00 (2006.01); C12P 21/00 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP US)
C07H 3/06 (2013.01 - EP); C07H 13/04 (2013.01 - EP); C07H 15/04 (2013.01 - EP); C07H 15/10 (2013.01 - EP); C07K 16/12 (2013.01 - EP); C07K 16/20 (2013.01 - EP); C07K 16/40 (2013.01 - EP); C12N 9/1081 (2013.01 - EP); C12P 19/00 (2013.01 - EP); C12P 21/005 (2013.01 - EP); A61K 39/00 (2013.01 - EP US); Y02A 50/30 (2018.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9318787 A1 19930930; AU 3937593 A 19931021; EP 0586687 A1 19940316; EP 0586687 A4 19960417
DOCDB simple family (application)
US 9302869 W 19930325; AU 3937593 A 19930325; EP 93908615 A 19930325