EP 0588785 A1 19940330 - UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS.
Title (en)
UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS.
Title (de)
AUF HARNSTOFF BASIERTE LIPOXYGENASE INHIBIERENDE VERBINDUNGEN.
Title (fr)
COMPOSES A BASE D'UREE INHIBITEURS DE LIPOXYGENASE.
Publication
Application
Priority
US 33156689 A 19890330
Abstract (en)
[origin: WO9012008A1] Substituted phenyl, naphthyl, and thienyl N-hydroxy urea compounds form a class of potent inhibitors of 5- and 12-lipoxygenase and are thus useful compounds in the treatment of inflammatory disease states where leukotrienes and other products of lipoxygenase enzyme activity are implicated.
Abstract (fr)
L'invention concerne des composés d'urée N-hydroxy de phényle, naphtyle et thiényle à substitution, formant une classe d'inhibiteurs puissants de lipoxygénase 5 et 12, utiles dans le traitement d'états inflammatoires dans lesquels des leucotriènes ainsi que d'autres produits présentant une activité enzymatique de lipoxygénase sont impliqués.
IPC 1-7
IPC 8 full level
C12N 9/99 (2006.01); A61K 31/17 (2006.01); A61K 31/195 (2006.01); A61K 31/22 (2006.01); A61K 31/275 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07C 275/64 (2006.01); C07C 323/44 (2006.01); C07C 323/47 (2006.01); C07C 335/40 (2006.01); C07D 333/20 (2006.01); C07D 333/22 (2006.01); C07D 333/28 (2006.01); C07D 333/32 (2006.01); C07D 333/36 (2006.01); C07D 335/08 (2006.01); C07D 409/04 (2006.01); C07D 409/06 (2006.01); C07D 409/12 (2006.01)
CPC (source: EP)
A61P 29/00 (2017.12); A61P 37/00 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12); C07C 275/64 (2013.01); C07C 323/47 (2013.01); C07D 333/36 (2013.01); C07D 335/08 (2013.01); C07D 409/04 (2013.01); C07D 409/06 (2013.01); C07D 409/12 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 9012008 A1 19901018; CA 2050597 A1 19901001; EP 0588785 A1 19940330; EP 0588785 A4 19911230; GR 900100231 A 19910731; JP H04504261 A 19920730
DOCDB simple family (application)
US 9001488 W 19900320; CA 2050597 A 19900320; EP 90906504 A 19900320; GR 900100231 A 19900328; JP 50610190 A 19900320