EP 0590057 A1 19940406 - MIMIC PEPTIDES OF gp120.
Title (en)
MIMIC PEPTIDES OF gp120.
Title (de)
GP-120-NACHAHMENDE PEPTIDE.
Title (fr)
PEPTIDES MIMANT LA gp120.
Publication
Application
Priority
- US 9204972 W 19920619
- US 71740091 A 19910619
- US 72906491 A 19910712
Abstract (en)
[origin: WO9222579A1] Disclosed are peptides having a primary amino acid sequence which is unrelated to gp120. The peptides are characterized by the ability to stimulate the production of anti-gp120, particularly anti-V3-loop, antibodies when administered to a mammal. The peptides are also characterized by the ability to interfere with viral function. The peptides can be formulated as a vaccine composition and administered as a method for stimulating an HIV-1 neutralizing immune response.
Abstract (fr)
Cette invention concerne des peptides comprenant une séquence primaire d'aides aminés qui n'est pas liée à la gp120. Les peptides se caractérisent par leur aptitude à stimuler la production d'anticorps anti-gp120, plus particulièrement d'anticorps anti-boucle-V3 lorsqu'on les administre à un mammifère. Ces peptides se caractérisent également par leur capacité à entraver avec la fonction virale. On peut formuler lesdits peptides sous forme d'une composition vaccinale et les administrer pour stimuler la réponse immunitaire neutralisant le VIH-1.
IPC 1-7
C07K 13/00; C07K 7/00; A61K 37/02; G01N 33/543; G01N 33/53; G01N 33/68; G01N 33/569; C12N 15/10
IPC 8 full level
C07K 14/16 (2006.01); C12N 15/10 (2006.01); C40B 40/02 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
C07K 14/005 (2013.01); C12N 15/1037 (2013.01); C40B 40/02 (2013.01); G01N 33/54393 (2013.01); G01N 33/56988 (2013.01); A61K 39/00 (2013.01); C12N 2740/16122 (2013.01)
Designated contracting state (EPC)
DE FR GB IT NL
DOCDB simple family (publication)
WO 9222579 A1 19921223; CA 2111681 A1 19921223; EP 0590057 A1 19940406
DOCDB simple family (application)
US 9204972 W 19920619; CA 2111681 A 19920619; EP 92914211 A 19920619