EP 0591408 A4 19961127 - TREATMENT OF DISEASES BY SITE-SPECIFIC INSTILLATION OF CELLS OR SITE-SPECIFIC TRANSFORMATION OF CELLS AND KITS THEREFOR
Title (en)
TREATMENT OF DISEASES BY SITE-SPECIFIC INSTILLATION OF CELLS OR SITE-SPECIFIC TRANSFORMATION OF CELLS AND KITS THEREFOR
Publication
Application
Priority
- US 9205243 W 19920626
- US 72450991 A 19910628
Abstract (en)
[origin: WO9300052A1] A method for the direct treatment towards the specific sites of a disease is disclosed. This method is based on the delivery of proteins by catheterization to discrete blood vessel segments using genetically modified or normal cells or other vector systems. Endothelial cells expressing recombinant therapeutic agent or diagnostic proteins are situated on the walls of the blood vessel or in the tissue perfused by the vessel in a patient. This technique provides for the transfer of cells or vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of diseases.
IPC 1-7
A61F 2/06; A61M 29/02; A61K 37/54; A61K 37/02; A61K 39/10; A61K 39/106; A61K 31/70; A61K 48/00
IPC 8 full level
A61K 31/70 (2006.01); A61B 17/22 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/715 (2006.01); A61K 35/14 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 38/27 (2006.01); A61K 38/46 (2006.01); A61K 39/00 (2006.01); A61K 47/42 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); A61L 29/16 (2006.01); A61M 25/00 (2006.01); A61P 3/08 (2006.01); A61P 3/10 (2006.01); A61P 7/02 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); C12M 1/00 (2006.01); C12N 5/07 (2010.01); C12N 5/077 (2010.01); C12N 5/0786 (2010.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP US)
A61B 17/22 (2013.01 - EP US); A61K 9/0024 (2013.01 - EP US); A61K 39/00 (2013.01 - EP US); A61K 47/6957 (2017.08 - EP US); A61K 48/00 (2013.01 - EP US); A61K 48/0075 (2013.01 - EP US); A61K 48/0083 (2013.01 - EP US); A61L 29/16 (2013.01 - EP US); A61P 3/08 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 7/02 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 31/12 (2018.01 - EP); A61P 31/18 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61B 2017/22082 (2013.01 - EP US); A61B 2017/22084 (2013.01 - EP US); A61L 2300/254 (2013.01 - EP US); A61L 2300/256 (2013.01 - EP US); A61L 2300/258 (2013.01 - EP US); A61L 2300/414 (2013.01 - EP US); A61L 2300/426 (2013.01 - EP US); A61L 2300/64 (2013.01 - EP US); A61L 2300/802 (2013.01 - EP US)
Citation (search report)
[XLY] WO 9011734 A1 19901018 - UNIV MICHIGAN [US]
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9300052 A1 19930107; CA 2112375 A1 19930107; DE 69233725 D1 20080327; DE 69233725 T2 20090212; EP 0591408 A1 19940413; EP 0591408 A4 19961127; JP H06509329 A 19941020
DOCDB simple family (application)
US 9205243 W 19920626; CA 2112375 A 19920626; DE 69233725 T 19920626; EP 92914489 A 19920626; JP 50159193 A 19920626