Global Patent Index - EP 0594311 B1

EP 0594311 B1 20011219 - Process for preparing a metastasis-inhibiting protein and uses thereof.

Title (en)

Process for preparing a metastasis-inhibiting protein and uses thereof.

Title (de)

Herstellung und Benützung eines Metastasehemmendes Proteines.

Title (fr)

Procédé de preparation et usages d'une protéine inhibitrice de metastases.

Publication

EP 0594311 B1 20011219 (EN)

Application

EP 93307668 A 19930928

Priority

JP 28113692 A 19920928

Abstract (en)

[origin: EP0594311A1] Disclosed is a novel protein which has a molecular weight of 45,000+/-5,000 and pI 5.7+/-0.5 and exhibits cancer metastasis-inhibitory activity. The protein can be prepared by culturing human cells, animal cells and microorganisms capable of producing the protein in a nutrient culture medium while stimulating them with an inducer such as Bacille Calmette-Guérin and lipopolysaccharide.

IPC 1-7

C12N 15/12; C07K 14/82; C12P 21/00

IPC 8 full level

A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C07K 14/47 (2006.01); C12N 5/07 (2010.01); C12N 5/0783 (2010.01); C12N 5/09 (2010.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12R 1/91 (2006.01)

CPC (source: EP KR US)

A61P 35/00 (2017.12 - EP); A61P 35/04 (2017.12 - EP); C07K 14/00 (2013.01 - KR); C07K 14/4703 (2013.01 - EP US); C12N 5/0694 (2013.01 - KR); A61K 38/00 (2013.01 - EP US); C12N 2500/72 (2013.01 - KR); C12N 2501/052 (2013.01 - KR)

Designated contracting state (EPC)

DE FR GB

DOCDB simple family (publication)

EP 0594311 A1 19940427; EP 0594311 B1 20011219; DE 69331368 D1 20020131; DE 69331368 T2 20020808; JP 3439490 B2 20030825; JP H06107693 A 19940419; KR 100294977 B1 20010917; KR 940007056 A 19940426; TW 241268 B 19950221; US 5498697 A 19960312; US 5585474 A 19961217; US 5827691 A 19981027

DOCDB simple family (application)

EP 93307668 A 19930928; DE 69331368 T 19930928; JP 28113692 A 19920928; KR 930019832 A 19930927; TW 82107913 A 19930925; US 12727893 A 19930927; US 55586095 A 19951113; US 82786497 A 19970409