Global Patent Index - EP 0608210 A4

EP 0608210 A4 19930607 - MUTAGENESIS TESTING USING TRANSGENIC NON-HUMAN ANIMALS CARRYING TEST DNA SEQUENCES.

Title (en)

MUTAGENESIS TESTING USING TRANSGENIC NON-HUMAN ANIMALS CARRYING TEST DNA SEQUENCES.

Title (de)

MUTAGENESETEST UNTER VERWENDUNG VON NICHTMENSCHLICHEN LEBEWESEN, DIE TEST DNA-SEQUENZEN ENTHALTEN.

Title (fr)

TEST DE MUTAGENESE A L'AIDE D'ANIMAUX TRANSGENIQUES PORTEURS DE SEQUENCES D'ADN TESTS.

Publication

EP 0608210 A4 19930607 (EN)

Application

EP 91908707 A 19910405

Priority

  • US 9102364 W 19910405
  • US 50567690 A 19900405

Abstract (en)

[origin: WO9115579A1] An assay for monitoring and assessing the mutagenic potential of agents which involves creating transgenic non-human animals carrying a test DNA sequence or sequences that can be quickly recovered and examined for mutations following exposure to one or more suspected mutagenic agents.

IPC 1-7

C12N 15/00; A01K 67/027; A61K 49/00; G01N 33/50

IPC 8 full level

A01K 67/027 (2006.01); C12N 15/85 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); G01N 33/50 (2006.01)

CPC (source: EP)

A01K 67/0275 (2013.01); C12N 15/8509 (2013.01); C12Q 1/6897 (2013.01); G01N 33/5017 (2013.01); A01K 2217/05 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0393 (2013.01); C12N 2800/30 (2013.01)

Citation (search report)

  • [XD] EP 0289121 A2 19881102 - STRATAGENE INC [US]
  • [YP] EP 0370813 A2 19900530 - TRANSGENIC SCIENCES INC [US]
  • [E] WO 9217605 A1 19921015 - INGENY BV [NL]
  • [X] JOURNAL OF CELLULAR BIOCHEMISTRY. vol. SUPPL, no. 13B, 21 January 1989, NEW YORK, USA page 184 SHORT, J.M. ET AL. 'The effects of eukaryotic methylation on recovery of a Lambda phage shuttle vector from transgenic mice'
  • [T] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA. vol. 88, no. 18, September 1991, WASHINGTON US pages 7958 - 7962 KOHLER, S.W. ET AL. 'Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice'
  • [XP] NUCLEIC ACIDS RESEARCH. vol. 18, no. 10, 25 May 1990, ARLINGTON, VIRGINIA US pages 3007 - 3013 KOHLER, S.W. ET AL. 'Development of a short-term, in vivo mutagenesis assay: the effects of methylation on the recovery of a lambda shuttle vector from transgenic mice'
  • See references of WO 9115579A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

WO 9115579 A1 19911017; CA 2079792 A1 19911006; EP 0608210 A1 19940803; EP 0608210 A4 19930607; JP H06506103 A 19940714

DOCDB simple family (application)

US 9102364 W 19910405; CA 2079792 A 19910405; EP 91908707 A 19910405; JP 50832891 A 19910405