EP 0619731 B1 20001004 - MICROCRYSTALLINE CELLULOSE SPHERONIZATION COMPOSITION
Title (en)
MICROCRYSTALLINE CELLULOSE SPHERONIZATION COMPOSITION
Title (de)
ZUSAMMENSETZUNG AUF DER BASIS VON MIKROKRISTALLINER ZELLULOSE FÜR DIE HERSTELLUNG VON KUGELFÖRMIGEN TEILCHEN
Title (fr)
COMPOSITION DE SPHERONISATION A BASE DE CELLULOSE MICROCRISTALLINE
Publication
Application
Priority
- US 81602791 A 19911230
- US 9209983 W 19921118
Abstract (en)
[origin: US5725886A] A particulate co-processed unattrited microcrystalline cellulose:hydrocolloid composition wherein the respective components are present in a weight ratio of from about 99:1 to 70:30. The composition is useful as a spheronizing agent for producing spheroids of uniform size and sphericity and having high drug loadings. The composition is produced by drying a slurry of the microcrystalline cellulose in an aqueous solution of the hydrocolloid. The preferred hydrocolloid is methylcellulose.
IPC 1-7
IPC 8 full level
A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 47/40 (2006.01); C08J 3/00 (2006.01); C08L 1/00 (2006.01); C08L 1/02 (2006.01); C08L 1/08 (2006.01); C08L 1/28 (2006.01)
CPC (source: EP US)
A61K 9/1652 (2013.01 - EP US); C08J 3/005 (2013.01 - EP US); C08L 1/02 (2013.01 - EP US); C08J 2300/14 (2013.01 - EP US); C08J 2301/00 (2013.01 - EP US); C08L 1/28 (2013.01 - EP US)
C-Set (source: EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE
DOCDB simple family (publication)
US 5725886 A 19980310; AT E196733 T1 20001015; AU 3179393 A 19930728; AU 663146 B2 19950928; BR 9206996 A 19951205; CA 2126441 A1 19930708; CA 2126441 C 19991221; CN 1074228 A 19930714; DE 69231499 D1 20001109; DE 69231499 T2 20010503; EP 0619731 A1 19941019; EP 0619731 A4 19950503; EP 0619731 B1 20001004; ES 2150438 T3 20001201; FI 943121 A0 19940629; FI 943121 A 19940629; IL 104087 A0 19930513; IL 104087 A 19981030; JP 2628230 B2 19970709; JP H06511255 A 19941215; MX 9207438 A 19930601; NO 942457 D0 19940629; NO 942457 L 19940629; WO 9312768 A1 19930708; ZA 929161 B 19930525
DOCDB simple family (application)
US 31180094 A 19940926; AT 93900553 T 19921118; AU 3179393 A 19921118; BR 9206996 A 19921118; CA 2126441 A 19921118; CN 92115100 A 19921221; DE 69231499 T 19921118; EP 93900553 A 19921118; ES 93900553 T 19921118; FI 943121 A 19940629; IL 10408792 A 19921214; JP 51164793 A 19921118; MX 9207438 A 19921218; NO 942457 A 19940629; US 9209983 W 19921118; ZA 929161 A 19921125