Global Patent Index - EP 0625909 A4

EP 0625909 A4 19970305 - AUTOANTIBODY ASSAY AND USAGE IN THE CONTROL OF HUMAN DISEASE.

Title (en)

AUTOANTIBODY ASSAY AND USAGE IN THE CONTROL OF HUMAN DISEASE.

Publication

EP 0625909 A4 19970305 (EN)

Application

EP 93904802 A 19930201

Priority

  • US 9300886 W 19930201
  • US 83569692 A 19920212

Abstract (en)

[origin: WO9315759A1] Methods of assay for and therapeutic use of autoantibodies, specifically anti-thymocyte autoantibody (ATAA). This is a teaching of methods for the assay of autoantibodies and for ATAA use, based upon autoantibody quantity in relation to a target lymphocyte population, for predicting body resistivity/susceptibility to disease and tumors, as well as suggesting protocols for the treatment of various diseases, malignancies and autoimmune reactions. The main thrust of the disclosure is the inventor's thesis that, by altering the amount of autoantibodies (in sera) which regulates the target cell population, diseases and/or malignancies may be eliminated or otherwise controlled.

IPC 1-7

A61K 39/00; G01N 33/564

IPC 8 full level

C07K 14/705 (2006.01); C07K 16/28 (2006.01); G01N 33/53 (2006.01); G01N 33/564 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

C07K 14/705 (2013.01); C07K 16/28 (2013.01); G01N 33/564 (2013.01); A61K 38/00 (2013.01); G01N 2800/24 (2013.01)

Citation (search report)

  • [A] J.P.W. VAN DER VEEN ET AL.: "Disease caused by reactions of T lymphocytes to incompatible structures of the major histocompatibility complex. III. Autoantibodies to thymocytes.", JOURNAL OF IMMUNOLOGY, vol. 127, no. 4, 1981, BETHESDA MD USA, pages 1281 - 1286, XP000611468
  • [A] R.J. WINCHESTER ET AL.: "Studies on antilymphocyte antibodies in patients with rheumatoid arthritis and systemic lupus erythematosus.", RHEUMATOLOGY, vol. 6, 1975, NEW YORK NY USA, pages 209 - 214, XP000610507
  • [A] E. FAGIOLO: "Thymocyteptoxic antibodies in patients with autoimmune hemolytic anemia systemic lupus erythematosus and lymphoproliferative diseases.", BLUT, vol. 44, no. 4, 1982, BERLIN FRG, pages 225 - 230, XP000610510
  • See references of WO 9315759A1

Designated contracting state (EPC)

AT DE FR GB IT

DOCDB simple family (publication)

WO 9315759 A1 19930819; AU 3603893 A 19930903; CA 2129895 A1 19930813; EP 0625909 A1 19941130; EP 0625909 A4 19970305; JP H07504495 A 19950518

DOCDB simple family (application)

US 9300886 W 19930201; AU 3603893 A 19930201; CA 2129895 A 19930201; EP 93904802 A 19930201; JP 51413393 A 19930201