EP 0626953 A4 19950503 - NOVEL SIDECHAIN-BEARING TAXANES AND INTERMEDIATES THEREOF.
Title (en)
NOVEL SIDECHAIN-BEARING TAXANES AND INTERMEDIATES THEREOF.
Title (de)
NEUE SEITENKETTEN TRAGENDE TAXANE UND IHRE ZWISCHENPRODUKTE.
Title (fr)
NOUVEAUX TAXANES A CHAINES LATERALES ET LEURS INTERMEDIAIRES.
Publication
Application
Priority
- US 9312173 W 19931215
- US 99544392 A 19921223
Abstract (en)
[origin: EP1251127A1] Novel methods for the preparation of sidechain-bearing taxanes, comprising the preparation of an oxazoline compound, coupling the oxazoline compound with a taxane having a hydroxyl group directly bonded at C-13 thereof to form an oxazoline sidechain-bearing taxane, and opening the oxazoline ring of the oxazoline sidechain-bearing taxane so formed. Novel compounds prepared by the methods of the present invention are also provided.
IPC 1-7
IPC 8 full level
C07C 233/17 (2006.01); A61K 31/337 (2006.01); A61K 31/42 (2006.01); A61P 35/00 (2006.01); C07C 233/30 (2006.01); C07C 233/45 (2006.01); C07C 233/82 (2006.01); C07C 271/22 (2006.01); C07C 309/66 (2006.01); C07C 309/73 (2006.01); C07D 263/06 (2006.01); C07D 263/14 (2006.01); C07D 263/16 (2006.01); C07D 305/14 (2006.01); C07D 307/54 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07F 7/18 (2006.01)
IPC 8 main group level
CPC (source: EP KR)
A61P 35/00 (2018.01 - EP); C07C 233/82 (2013.01 - EP); C07C 271/22 (2013.01 - EP); C07D 263/06 (2013.01 - EP); C07D 263/16 (2013.01 - EP); C07D 305/14 (2013.01 - EP KR); C07D 407/12 (2013.01 - EP); C07D 409/12 (2013.01 - EP); C07D 413/04 (2013.01 - EP); C07D 413/12 (2013.01 - EP); C07D 413/14 (2013.01 - EP); Y02P 20/55 (2015.11 - EP)
Citation (search report)
No further relevant documents disclosed
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9414787 A1 19940707; AT E309229 T1 20051115; AU 3246397 A 19971030; AU 3246497 A 19971009; AU 6014694 A 19940719; AU 679206 B2 19970626; AU 697836 B2 19981015; AU 715633 B2 20000210; CA 2119261 A1 19940624; CA 2119261 C 20060131; CN 1089761 C 20020828; CN 1094725 A 19941109; CN 1109026 C 20030521; CN 1150178 C 20040519; CN 1230542 A 19991006; CN 1235973 A 19991124; CN 1590386 A 20050309; CZ 146594 A3 19950614; CZ 292993 B6 20040114; DE 69333905 D1 20051215; DE 69333905 T2 20060803; DK 1251127 T3 20060306; EP 0626953 A1 19941207; EP 0626953 A4 19950503; EP 1251127 A1 20021023; EP 1251127 B1 20051109; ES 2252362 T3 20060516; FI 115056 B 20050228; FI 20031464 A 20031007; FI 943852 A0 19940822; FI 943852 A 19940822; HK 1048310 A1 20030328; HK 1048310 B 20060217; HU 0203995 D0 20030428; HU 222175 B1 20030428; HU 225294 B1 20060928; HU 9401449 D0 19940928; HU T75195 A 19970428; IL 108161 A0 19940412; IL 108161 A 19990312; IL 121539 A0 19980208; IL 121539 A 20040725; IL 121540 A0 19980208; IL 121540 A 20050517; IL 121541 A0 19980208; IL 121541 A 20001121; IL 121542 A0 19980208; IL 121542 A 20010319; IL 122208 A0 19980405; IL 122209 A0 19980405; IL 145280 A0 20020630; IL 145280 A 20070515; JP 2003113166 A 20030418; JP 3492690 B2 20040203; JP H07504444 A 19950518; KR 100327625 B1 20021107; KR 100356448 B1 20021019; KR 100378612 B1 20030403; KR 950700269 A 19950116; NO 20033865 D0 20030901; NO 20033865 L 19940816; NO 304521 B1 19990104; NO 309426 B1 20010129; NO 311217 B1 20011029; NO 313802 B1 20021202; NO 314355 B1 20030310; NO 316071 B1 20031208; NO 943021 D0 19940816; NO 943021 L 19940816; NO 973253 D0 19970714; NO 973253 L 19940816; NO 973254 D0 19970714; NO 973254 L 19940816; NO 973255 D0 19970714; NO 973255 L 19940816; NO 973256 D0 19970714; NO 973256 L 19940816; NO 982744 D0 19980615; NO 982744 L 19940816; NZ 261070 A 19971024; PL 186176 B1 20031128; RU 2125042 C1 19990120; TW 247908 B 19950521; ZA 939672 B 19950623
DOCDB simple family (application)
US 9312173 W 19931215; AT 02014813 T 19931215; AU 3246397 A 19970804; AU 3246497 A 19970804; AU 6014694 A 19931215; CA 2119261 A 19931215; CN 03108243 A 19931223; CN 93121758 A 19931223; CN 99101065 A 19990112; CN 99101066 A 19990112; CZ 146594 A 19931215; DE 69333905 T 19931215; DK 02014813 T 19931215; EP 02014813 A 19931215; EP 94906439 A 19931215; ES 02014813 T 19931215; FI 20031464 A 20031007; FI 943852 A 19940822; HK 03100278 A 20030110; HU 0203995 A 19931215; HU 2003995 A 19931215; HU 9401449 A 19931215; IL 10816193 A 19931223; IL 12153993 A 19931223; IL 12153997 A 19970813; IL 12154093 A 19931223; IL 12154097 A 19970813; IL 12154193 A 19931223; IL 12154197 A 19970813; IL 12154293 A 19931223; IL 12154297 A 19970813; IL 12220897 A 19971116; IL 12220997 A 19971116; IL 14528001 A 20010904; IL 14528093 A 19931223; JP 2002267305 A 20020912; JP 51526694 A 19931215; KR 19940702930 A 19940823; KR 20017008427 A 20010630; KR 20027002728 A 20020228; NO 20033865 A 20030901; NO 943021 A 19940816; NO 973253 A 19970714; NO 973254 A 19970714; NO 973255 A 19970714; NO 973256 A 19970714; NO 982744 A 19980615; NZ 26107093 A 19931215; PL 30433793 A 19931215; RU 94040189 A 19931215; TW 82110923 A 19931223; ZA 939672 A 19931223