EP 0628167 B1 20000823 - HEMATOLOGY CONTROL COMPOSITION FOR LEUKOCYTE ANALOGS; AND METHODS FOR THEIR PREPARATION AND USE
Title (en)
HEMATOLOGY CONTROL COMPOSITION FOR LEUKOCYTE ANALOGS; AND METHODS FOR THEIR PREPARATION AND USE
Title (de)
Hämatologisches Kontrollprodukt mit Leukozytenanalogen; und Methoden zu ihrer Herstellung und Anwendung
Title (fr)
COMPOSITION DE CONTROLE HEMATOLOGIQUE POUR ANALOGUES LEUCOCYTAIRES, METHODE DE PREPARATION ET UTILISATION
Publication
Application
Priority
- US 9301855 W 19930217
- US 84043592 A 19920224
Abstract (en)
[origin: US5320964A] A hematology control product comprising leukocyte analogs is described. The analogs comprise red blood cells which simulate at least two physical properties of human leukocytes. A method for making leukocyte analogs from blood cells having desired physical properties is also described. The process comprises expanding the cell volume, changing the hemoglobin content of the cell and fixing the cell. Generally, the monocyte and lymphocyte analogs leak hemoglobin from the cell while the eosinophil analog has the hemoglobin precipitated in the cell. A further method is described to use the control product to determine whether an automatic instrument is operating within manufacturer's specification.
IPC 1-7
IPC 8 full level
G01N 33/49 (2006.01); G01N 33/50 (2006.01); G01N 33/96 (2006.01)
CPC (source: EP US)
G01N 33/96 (2013.01 - EP US); G01N 2496/05 (2013.01 - EP US); Y10T 436/101666 (2015.01 - EP US); Y10T 436/102499 (2015.01 - EP US); Y10T 436/105831 (2015.01 - EP US); Y10T 436/106664 (2015.01 - EP US); Y10T 436/107497 (2015.01 - EP US); Y10T 436/108331 (2015.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9317330 A1 19930902; AT E195810 T1 20000915; AU 3736693 A 19930913; AU 665413 B2 19960104; BR 9305952 A 19971021; CA 2129832 A1 19930825; DE 69329274 D1 20000928; DE 69329274 T2 20010412; EP 0628167 A1 19941214; EP 0628167 A4 19961030; EP 0628167 B1 20000823; JP 3391451 B2 20030331; JP H07504038 A 19950427; KR 950700539 A 19950116; NO 943115 D0 19940823; NO 943115 L 19940901; US 5320964 A 19940614; US 5512485 A 19960430
DOCDB simple family (application)
US 9301855 W 19930217; AT 93906274 T 19930217; AU 3736693 A 19930217; BR 9305952 A 19930217; CA 2129832 A 19930217; DE 69329274 T 19930217; EP 93906274 A 19930217; JP 51512093 A 19930217; KR 19940702936 A 19940823; NO 943115 A 19940823; US 34299794 A 19941121; US 8175293 A 19930623