Global Patent Index - EP 0633943 A4

EP 0633943 A4 19970502 - GENE THERAPY USING TARGETED VIRAL VECTORS.

Title (en)

GENE THERAPY USING TARGETED VIRAL VECTORS.

Title (de)

GENTHERAPY UNTER VERWENDUNG ZIELGERICHTETER VIRALER VEKTOREN.

Title (fr)

THERAPIE GENIQUE UTILISANT DES VECTEURS VIRAUX CIBLES.

Publication

EP 0633943 A4 19970502 (EN)

Application

EP 93908659 A 19930331

Priority

  • US 9302957 W 19930331
  • US 86279592 A 19920403
  • US 4074893 A 19930329

Abstract (en)

[origin: WO9320221A1] A general method for delivering genes to specific target cells in vivo is described. Enveloped viruses are genetically engineered to infect specific target cells by replacing the cell surface receptor recognition domain of viral envelope proteins with ligands that direct the binding and fusion of these viruses to specific cell surface molecules.

IPC 1-7

C12N 15/86; A61K 49/00

IPC 8 full level

A61K 31/70 (2006.01); A61K 35/76 (2006.01); A61K 48/00 (2006.01); C12N 15/09 (2006.01); C12N 15/867 (2006.01)

CPC (source: EP)

C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13045 (2013.01); C12N 2810/854 (2013.01); C12N 2810/855 (2013.01); C12N 2810/856 (2013.01); C12N 2810/859 (2013.01)

Citation (search report)

  • [X] WO 9012087 A1 19901018 - NOVACELL CORP [US]
  • [X] WO 9102805 A2 19910307 - VIAGENE INC [US]
  • [A] WO 9205266 A2 19920402 - VIAGENE INC [US]
  • [PX] WO 9214829 A1 19920903 - UNIV CALIFORNIA [US], et al
  • [PX] WO 9300103 A1 19930107 - WISTAR INST [US], et al
  • [PX] WO 9305147 A1 19930318 - US HEALTH [US]
  • [PX] WO 9314188 A1 19930722 - UNIV MICHIGAN [US]
  • [X] A. MARTIN ET AL.: "Engineering a poliovirus type 2 antigenic site on a type 1 capsid results in a chimaeric virus which is neurivirulent for mice", EMBO J., vol. 7, no. 9, September 1988 (1988-09-01), OXFORD UNIVERSITY PRESS,GB;, pages 2839 - 2847, XP002025309
  • [X] S.D. LONDON ET AL.: "Infectious enveloped RNA virus antigenic chimeras", PROC. NATL.ACAD SCI., vol. 89, January 1992 (1992-01-01), NATL. ACAD SCI.,WASHINGTON,DC,US;, pages 207 - 211, XP002025310
  • [A] B. GOUD ET AL.: "Antibody-mediated binding of a murine ecotropic miloney retroviral vector to human cells allows internalization but not the establishment of the proviral state", VIROLOGY, vol. 163, no. 3, March 1988 (1988-03-01), ACADEMIC PRESS, INC.,NEW YORK, US, pages 251 - 254, XP000613633
  • [A] HIROSHI NEDA ET AL: "CHEMICAL MODIFICATION OF AN ECOTROPIC MURINE LEUKEMIA VIRUS RESULTS IN REDIRECTION OF ITS TARGET CELL SPECIFICITY", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, no. 22, 5 August 1991 (1991-08-05), pages 14143 - 14146, XP000612122
  • [PX] DONG J ET AL: "A CHIMERIC AVIAN RETROVIRUS CONTAINING THE INFLUENZA VIRUS HEMAGGLUTININ GENE HAS AN EXPANDED HOST RANGE", JOURNAL OF VIROLOGY, vol. 66, no. 12, 1 December 1992 (1992-12-01), pages 7374 - 7382, XP002011560
  • See references of WO 9320221A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9320221 A1 19931014; AU 3940293 A 19931108; CA 2133411 A1 19931014; EP 0633943 A1 19950118; EP 0633943 A4 19970502; JP H07505773 A 19950629

DOCDB simple family (application)

US 9302957 W 19930331; AU 3940293 A 19930331; CA 2133411 A 19930331; EP 93908659 A 19930331; JP 51762693 A 19930331