EP 0636144 A1 19950201 - ALPHA-AMINOBORONIC ACID PEPTIDES AND THEIR USE AS ELASTASE INHIBITORS.
Title (en)
ALPHA-AMINOBORONIC ACID PEPTIDES AND THEIR USE AS ELASTASE INHIBITORS.
Title (de)
PEPTIDE MIT EINER ALPHAAMINOBORSAEUREGRUPPE UND IHRE VERWENDUNG ALS ELASTASEHEMMER.
Title (fr)
PEPTIDES D'ACIDE ALPHA-AMINOBORONIQUE ET LEUR UTILISATION COMME INHIBITEURS D'ELASTASE.
Publication
Application
Priority
- GB 9300796 W 19930415
- GB 9208387 A 19920416
- GB 9217366 A 19920814
Abstract (en)
[origin: WO9321213A1] The present invention relates to certain novel heterocyclic derivatives which are 1-pyridylacetamide derivatives of formula (I), set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases on mammals in which (HLE) is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic derivatives, processes for preparing the heterocyclic derivatives, pharmaceutical compositions containing such heterocyclic derivatives and methods for their use.
IPC 1-7
IPC 8 full level
A61K 38/55 (2006.01); A61P 7/02 (2006.01); A61P 9/00 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 29/00 (2006.01); C07K 5/06 (2006.01); C07K 5/078 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); A61P 9/00 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 11/00 (2017.12); A61P 29/00 (2017.12); C07K 5/06139 (2013.01); C07K 5/06191 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9321213A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9321213 A1 19931028; AU 4077193 A 19931118; CA 2133658 A1 19931028; EP 0636144 A1 19950201; JP H07505875 A 19950629
DOCDB simple family (application)
GB 9300796 W 19930415; AU 4077193 A 19930415; CA 2133658 A 19930415; EP 93910159 A 19930415; JP 51813993 A 19930415