EP 0639184 A1 19950222 - NEW QUINAZOLINES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE.
Title (en)
NEW QUINAZOLINES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE.
Title (de)
QUINAZOLINE ALS HIV-REVERSE TRANSCRIPTASE HEMMER.
Title (fr)
NOUVELLES QUINAZOLINES INHIBANT LA TRANSCRIPTASE INVERSE DU VIH.
Publication
Application
Priority
- US 9303975 W 19930428
- US 88011992 A 19920507
- US 99116492 A 19921216
Abstract (en)
[origin: EP0569083A1] Compounds having a quinazolin-2-one nucleus with a substituted alkynyl or substituted alkenyl at the 4-position are described. These compounds are useful in the inhibition of HIV reverse transcriptase (including its resistant varieties), the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
IPC 1-7
C07D 239/80; A61K 31/505; C07D 401/06; C07D 403/06; C07D 405/12; C07D 401/12; A61K 31/70
IPC 8 full level
A61K 31/505 (2006.01); A61K 31/517 (2006.01); A61P 31/12 (2006.01); C07D 239/80 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/06 (2006.01); C07D 405/12 (2006.01)
IPC 8 main group level
C07D 471/00 (2006.01)
CPC (source: EP)
A61P 31/12 (2017.12); C07D 239/80 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/06 (2013.01); C07D 405/12 (2013.01)
Citation (search report)
See references of WO 9322292A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
EP 0569083 A1 19931110; AU 3841393 A 19931111; AU 4220493 A 19931129; BG 99149 A 19950630; CA 2095194 A1 19931108; CN 1085550 A 19940420; CZ 272494 A3 19951018; EP 0639184 A1 19950222; FI 945199 A0 19941104; FI 945199 A 19941104; HR P930857 A2 19950630; HU T71401 A 19951128; IL 105551 A0 19930818; JP H069578 A 19940118; JP H0813805 B2 19960214; KR 950701322 A 19950323; MX 9302681 A 19940531; SI 9300244 A 19931231; WO 9322292 A1 19931111
DOCDB simple family (application)
EP 93201232 A 19930429; AU 3841393 A 19930506; AU 4220493 A 19930428; BG 9914994 A 19941031; CA 2095194 A 19930429; CN 93107074 A 19930506; CZ 272494 A 19930428; EP 93910860 A 19930428; FI 945199 A 19941104; HR P930857 A 19930505; HU 9403187 A 19930428; IL 10555193 A 19930429; JP 10701593 A 19930507; KR 19940703948 A 19941105; MX 9302681 A 19930506; SI 9300244 A 19930507; US 9303975 W 19930428