EP 0642499 A1 19950315 - RETINOIDS AND THEIR USE IN TREATING SKIN DISEASES AND LEUKEMIA.
Title (en)
RETINOIDS AND THEIR USE IN TREATING SKIN DISEASES AND LEUKEMIA.
Title (de)
RETINOIDER UND IHRE VERWENDUNG BEI DER BEHANDLUNG VON HAUTKRANKHEITEN UND LEUKÄMIE.
Title (fr)
RETINOIDES ET LEUR UTILISATION POUR TRAITER DES MALADIES DE LA PEAU ET LA LEUCEMIE.
Publication
Application
Priority
- US 9206485 W 19920810
- US 76457891 A 19910924
Abstract (en)
[origin: WO9306086A1] Compounds of formula (I) or (II) and pharmaceutically acceptable salts and prodrugs thereof, wherein R<1> is C1 to C8 alkyl and Q is selected from (a), (b), (c), (d), (e) and (f), wherein Y is selected from (III), (IV), (V), (VI), (VII), (VIII), (IX) and (X) and Z is selected from groups of formula (XI), with the pharmaceutically acceptable salts and prodrugs of the aforesaid formula I or II final products being derived from the hereinbefore described Y and Z acid groups. These compounds are useful in treating aging skin, and also skin conditions such as psoriasis, acne and related disorder of keratinization and epithelial differentiation, as well as skin tumors.
IPC 1-7
C07D 213/80; A61K 31/44; A61K 31/235; C07C 69/86; C07C 69/017
IPC 8 full level
A61K 31/235 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61K 31/44 (2006.01); A61K 31/495 (2006.01); A61K 31/505 (2006.01); A61P 17/00 (2006.01); A61P 35/02 (2006.01); C07C 69/76 (2006.01); C07C 69/80 (2006.01); C07C 69/82 (2006.01); C07C 69/86 (2006.01); C07C 69/94 (2006.01); C07D 213/80 (2006.01); C07D 239/34 (2006.01); C07D 239/42 (2006.01); C07D 241/18 (2006.01); C07D 241/20 (2006.01); C07D 333/30 (2006.01)
CPC (source: EP)
A61P 17/00 (2017.12); A61P 35/02 (2017.12); C07C 69/82 (2013.01); C07C 69/86 (2013.01); C07D 213/80 (2013.01)
Citation (search report)
See references of WO 9306086A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL SE
DOCDB simple family (publication)
WO 9306086 A1 19930401; CA 2119571 A1 19930401; EP 0642499 A1 19950315; FI 941345 A0 19940323; FI 941345 A 19940323; JP H06507178 A 19940811; PT 100878 A 19931029
DOCDB simple family (application)
US 9206485 W 19920810; CA 2119571 A 19920810; EP 92917698 A 19920810; FI 941345 A 19940323; JP 50602492 A 19920810; PT 10087892 A 19920918