Global Patent Index - EP 0643586 A4

EP 0643586 A4 19960626 - COMPOSITIONS USEFUL IN DIAGNOSIS AND PROPHYLAXIS OF LYME DISEASE.

Title (en)

COMPOSITIONS USEFUL IN DIAGNOSIS AND PROPHYLAXIS OF LYME DISEASE.

Title (de)

ZUSAMMENSETZUNGEN NÜTZLICH IN DER DIAGNOSE UND PROPHYLAXE DER LYME KRANKHEIT.

Title (fr)

COMPOSITIONS UTILISEES DANS LE DIAGNOSTIC ET LA PROPHYLAXIE DE LA MALADIE DE LYME.

Publication

EP 0643586 A4 19960626 (EN)

Application

EP 93914155 A 19930526

Priority

  • US 9304984 W 19930526
  • US 88901592 A 19920526
  • US 94446492 A 19920914
  • US 99289692 A 19921218

Abstract (en)

[origin: WO9324145A1] The present invention provides novel isolated B. burgdorferi antigens which have been regulated and differentiated in a tick vector. These antigens are useful in diagnosing Lyme disease and in compositions for prophylaxis thereof.

IPC 1-7

A61K 39/00; A61K 39/02; C12Q 1/00; C07K 1/00

IPC 8 full level

G01N 33/569 (2006.01); A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/395 (2006.01); A61P 31/00 (2006.01); C07K 14/195 (2006.01); C07K 14/20 (2006.01); C07K 16/12 (2006.01); C12N 15/02 (2006.01); C12P 21/00 (2006.01); C12P 21/08 (2006.01); A61K 38/00 (2006.01); C12R 1/01 (2006.01); C12R 1/91 (2006.01)

CPC (source: EP)

A61K 39/0225 (2013.01); A61P 31/00 (2017.12); C07K 14/20 (2013.01); C07K 16/1207 (2013.01); A61K 38/00 (2013.01); Y02A 50/30 (2017.12)

Citation (search report)

  • [A] R.S. LANE ET AL.: "ANTIGENIC CHARACTERISTICS OF BORRELIA BURGDORFERI ISOLATES FROM IXODID TICKS IN CALIFORNIA.", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 27, no. 10, October 1989 (1989-10-01), WASHINGTON, D.C., US, pages 2344 - 2349, XP000568737
  • [A] E. FIKRIG ET AL.: "ROLES OF OspA, OspB, AND FLAGELLIN IN PROTECTIVE IMMUNITY TO LYME BORRELIOSIS IN LABORATORY MICE.", INFECTION AND IMMUNITY, vol. 60, no. 2, February 1992 (1992-02-01), WASHINGTON US, pages 657 - 661, XP002001270
  • [A] K. HANSEN ET AL.: "IMMUNOCHEMICAL CHARACTERIZATION OF AND ISOLATION OF THE GENE FOR A BORRELIA BURGDORFERI IMMUNODOMINANT 60-KILODALTON ANTIGEN COMMON TO A WIDE RANGE OF BACTERIA.", INFECTION AND IMMUNITY, vol. 56, no. 8, August 1988 (1988-08-01), WASHINGTON US, pages 2047 - 2053, XP002001271
  • [A] R. WALLICH ET AL.: "THE BORRELIA BURGDORFERI FLAGELLUM-ASSOCIATED 41-KILODALTON ANTIGEN (FLAGELLIN): MOLECULAR CLONING, EXPRESSION, AND AMPLIFICATION OF THE GENE.", INFECTION AND IMMUNITY, vol. 58, no. 6, June 1990 (1990-06-01), WASHINGTON US, pages 1711 - 1719, XP002001272
  • [A] V.G. BUNDOC ET AL.: "CLONAL POLYMORPHISMS OF THE OUTER MEMBRANE PROTEIN OspB OF BORRELIA BURGDORFERI.", INFECTION AND IMMUNITY, vol. 57, no. 9, September 1989 (1989-09-01), WASHINGTON US, pages 2733 - 2741, XP002001273
  • [A] J.L. BENACH ET AL.: "A MURINE IgM MONOCLONAL ANTIBODY BINDS AN ANTIGENIC DETERMINANT IN OUTER SURFACE PROTEIN A, AN IMMUNODOMINANT BASIC PROTEIN OF THE LYME DISEASE SPIROCHETE.", JOURNAL OF IMMUNOLOGY, vol. 140, no. 1, 1 January 1988 (1988-01-01), BALTIMORE US, pages 265 - 272, XP002001274
  • [PX] W.T. GOLDE ET AL.: "THE MAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED RESPONSE OF RECOMBINANT INBRED STRAINS OF MICE TO NATURAL TICK TRANSMISSION OF BORRELIA BURGDORFERI.", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 177, no. 1, January 1993 (1993-01-01), NEW YORK, N.Y., US, pages 9 - 17, XP000568811
  • [PX] J.T. ROEHRIG ET AL.: "THE HAMSTER IMMUNE RESPONSE TO TICK-TRANSMITTED BORRELIA BURGDORFERI DIFFERS FROM THE RESPONSE TO NEEDLE-INOCULATED, CULTURED ORGANISMS.", JOURNAL OF IMMUNOLOGY, vol. 149, no. 11, 1 December 1992 (1992-12-01), BALTIMORE US, pages 3648 - 3653, XP002001275
  • See references of WO 9324145A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9324145 A1 19931209; AU 4392093 A 19931230; CA 2135800 A1 19931209; EP 0643586 A1 19950322; EP 0643586 A4 19960626; JP H08503194 A 19960409

DOCDB simple family (application)

US 9304984 W 19930526; AU 4392093 A 19930526; CA 2135800 A 19930526; EP 93914155 A 19930526; JP 50072893 A 19930526