EP 0648265 A1 19950419 - METHODS FOR PRODUCING TRANSGENIC NON-HUMAN ANIMALS HARBORING A YEAST ARTIFICIAL CHROMOSOME.
Title (en)
METHODS FOR PRODUCING TRANSGENIC NON-HUMAN ANIMALS HARBORING A YEAST ARTIFICIAL CHROMOSOME.
Title (de)
METHODEN ZUR HERSTELLUNG VON NICHT-HUMANEN TRANSGENEN TIEREN DIE EIN ARTIFIZIELLES HEFE CHROMOSOM ENTHALTEN.
Title (fr)
PROCEDE DE PRODUCTION D'ANIMAUX TRANSGENIQUES NON-HUMAINS ABRITANT UN CHROMOSOME ARTIFICIEL DE LEVURE.
Publication
Application
Priority
- US 9305873 W 19930618
- US 90097292 A 19920618
- US 149393 A 19930107
Abstract (en)
[origin: WO9400569A1] The present invention provides methods and compositions for transferring large transgene polynucleotides and unlinked selectable marker polynucleotides into eukaryotic cells by a novel method designated co-lipofection. The methods and compositions of the invention are used to produce novel transgenic non-human animals harboring large transgenes, such as a transgene comprising a human APP gene or human immunoglobulin gene.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/85 (2006.01); C12N 15/88 (2006.01)
CPC (source: EP)
A01K 67/0276 (2013.01); A01K 67/0278 (2013.01); C07K 14/4711 (2013.01); C07K 16/00 (2013.01); C12N 15/8509 (2013.01); C12N 15/88 (2013.01); A01K 2207/15 (2013.01); A01K 2217/00 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0306 (2013.01); A01K 2267/0312 (2013.01); C07K 2317/21 (2013.01); C07K 2317/52 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9400569 A1 19940106; AU 4541093 A 19940124; CA 2135313 A1 19940106; EP 0648265 A1 19950419; EP 0648265 A4 19961204; JP H07508410 A 19950921; NZ 253943 A 19970129
DOCDB simple family (application)
US 9305873 W 19930618; AU 4541093 A 19930618; CA 2135313 A 19930618; EP 93915422 A 19930618; JP 50248394 A 19930618; NZ 25394393 A 19930618