Global Patent Index - EP 0650358 A1

EP 0650358 A1 19950503 - 17-ACYL-4-AZA-STEROID-3-ONE AS 5-ALPHA-REDUCTASE INHIBITORS.

Title (en)

17-ACYL-4-AZA-STEROID-3-ONE AS 5-ALPHA-REDUCTASE INHIBITORS.

Title (de)

17-ACYL-4-AZA-STEROID-3-ON-DERIVATE ALS 5-ALPHA-REDUCTASE-INHIBITOREN.

Title (fr)

17-ACYL-4-AZA-STEROIDE-3-ONE A TITRE D'INHIBITEURS DE 5-ALPHA-REDUCTASE.

Publication

EP 0650358 A1 19950503 (EN)

Application

EP 93916878 A 19930630

Priority

  • GB 9213901 A 19920630
  • US 9306233 W 19930630

Abstract (en)

[origin: WO9400121A1] Invented are 17(alpha) and 17(beta)-alkylketone-4-aza analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-(alpha)-reductase isozyme 1 and steroid 5-(alpha)-reductase isozyme 2. Also invented are proceses used in preparing these compounds.

[origin: WO9400121A1] Invented are 17 alpha and 17 beta -alkylketone-4-aza analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5- alpha -reductase isozyme 1 and steroid 5- alpha -reductase isozyme 2. Also invented are proceses used in preparing these compounds.

IPC 1-7

A61K 31/435; C07J 73/00

IPC 8 full level

A61K 31/505 (2006.01); A61K 31/58 (2006.01); C07J 73/00 (2006.01)

CPC (source: EP)

C07J 73/003 (2013.01); C07J 73/005 (2013.01)

Designated contracting state (EPC)

BE CH DE FR GB IT LI NL

DOCDB simple family (publication)

WO 9400121 A1 19940106; EP 0650358 A1 19950503; EP 0650358 A4 19950607; GB 9213901 D0 19920812; JP H07508524 A 19950921

DOCDB simple family (application)

US 9306233 W 19930630; EP 93916878 A 19930630; GB 9213901 A 19920630; JP 50265794 A 19930630