Global Patent Index - EP 0650974 A1

EP 0650974 A1 19950503 - Acylaminosaccharide derivative and process for preparing the same.

Title (en)

Acylaminosaccharide derivative and process for preparing the same.

Title (de)

Acylaminosaccharid-Derivate und Verfahren zur Herstellung.

Title (fr)

Dérivé d'acylaminosaccharide et son procédé de préparation.

Publication

EP 0650974 A1 19950503 (EN)

Application

EP 93308624 A 19931028

Priority

EP 93308624 A 19931028

Abstract (en)

There are disclosed an acylaminosaccharide derivative represented by the formula (I): <CHEM> wherein R<1> is H, aryl or heterocyclic; X is a mere bond, alkylene, alkenylene or alkynylene; R<2> is (1) H, (2) aryl or heterocyclic, (3) aryl lower alkylcarbamoyl, (4) substituted carbonyl, or (5) carboxyl which may be esterified; Y is a mere bond, alkylene, alkenylene, alkynylene or tricycloalkylene; R<3> and R<4> are different and either hydrogen, or lower alkoxy or phenoxy; R<5> and R<6> are different and either hydrogen or hydroxy; and when R<7> is hydroxy, R<8> and R<9> are different and either hydrogen or hydroxy, or when R<7> and R<8> are bonded to each other to form lower alkylenedioxy, R<9> is hydrogen, or a pharmaceutically acceptable salt thereof, and a process for preparing the same.

IPC 1-7

C07H 15/203; C07H 15/04; A61K 31/70; C07H 15/10; C07H 15/18; C07H 15/26; C07H 17/02; C07H 17/06

IPC 8 full level

C07H 15/12 (2006.01); C07H 15/18 (2006.01); C07H 15/203 (2006.01); C07H 15/26 (2006.01)

CPC (source: EP)

C07H 15/12 (2013.01); C07H 15/18 (2013.01); C07H 15/203 (2013.01); C07H 15/26 (2013.01)

Citation (search report)

  • [A] T. MORIKAWA ET AL: "A new class of nitrosoureas. IX. Synthesis and antitumor activity of 3-substituted 1-(2-chloroethyl)-3-(methyl-alpha-D-glucopyranosid-6-yl or methyl 2-acetamido-2-deoxy-alpha-D-glucopyranosid-6-yl)-1-nitrosoureas", CHEMICAL AND PHARMACEUTICAL BULLETIN, vol. 31, no. 11, November 1983 (1983-11-01), TOKYO JP, pages 3924 - 3930
  • [AD] T. D. INCH ET G. J. LEWIS: "Use of carbohydrate derivatives for studies of phosphorus stereochemistry. Part VI. A stereochemical comparison of S-alkyl alkylphosphonothioate-sodium methoxide and S-alkyl phosphorothioate-sodium methoxide reactions.", CARBOHYDRATE RESEARCH, vol. 45, 1975, AMESTERDAM, NL, pages 65 - 72

Designated contracting state (EPC)

DE FR GB IT

DOCDB simple family (publication)

EP 0650974 A1 19950503

DOCDB simple family (application)

EP 93308624 A 19931028