EP 0651643 A1 19950510 - 17-ALKYLKETONE STEROIDS USEFUL AS 5--g(a)-REDUCTASE INHIBITORS.
Title (en)
17-ALKYLKETONE STEROIDS USEFUL AS 5--g(a)-REDUCTASE INHIBITORS.
Title (de)
17-ALKYLKETONSTEROIDE ALS 5-ALPHA-REDUKTASE-INHIBITOREN.
Title (fr)
STEROIDES 17-AKYLCETONIQUES UTILES COMME INHIBITEURS DE 5--g(a)-REDUCTASE.
Publication
Application
Priority
- GB 9213835 A 19920630
- US 9306238 W 19930630
Abstract (en)
[origin: WO9400125A1] Invented are 17(alpha) and 17(beta)-alkylketone-3-carboxy aromatic A ring analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-(alpha)-reductase isozyme 1 and steroid 5-(alpha)-reductase isozyme 2. Also invented are intermediates and processes used in preparing these compounds.
[origin: WO9400125A1] Invented are 17 alpha and 17 beta -alkylketone-3-carboxy aromatic A ring analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5- alpha -reductase isozyme 1 and steroid 5- alpha -reductase isozyme 2. Also invented are intermediates and processes used in preparing these compounds.
IPC 1-7
A61K 31/565; A61K 31/57; A61K 31/575; C07J 1/00; C07J 5/00; C07J 7/00; C07J 9/00; C07J 75/00; C07J 31/00
IPC 8 full level
A61K 31/565 (2006.01); A61K 31/57 (2006.01); A61K 31/575 (2006.01); C07J 1/00 (2006.01); C07J 3/00 (2006.01); C07J 5/00 (2006.01); C07J 7/00 (2006.01); C07J 9/00 (2006.01); C07J 31/00 (2006.01); C07J 41/00 (2006.01)
IPC 8 main group level
C07C 69/00 (2006.01); C07J 63/00 (2006.01)
IPC 8 main group level
C07J (2006.01)
CPC (source: EP KR)
A61K 31/565 (2013.01 - KR); A61K 31/57 (2013.01 - EP KR); A61K 31/575 (2013.01 - EP); C07J 3/00 (2013.01 - EP); C07J 3/005 (2013.01 - EP); C07J 7/002 (2013.01 - EP); C07J 7/007 (2013.01 - EP); C07J 9/00 (2013.01 - EP); C07J 9/005 (2013.01 - EP); C07J 31/006 (2013.01 - EP); C07J 41/0094 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9400125 A1 19940106; AP 412 A 19950929; AP 9300542 A0 19930731; AU 4545993 A 19940124; BG 99313 A 19950929; BR 9306748 A 19981208; CA 2138956 A1 19940106; CN 1095382 A 19941123; CZ 334694 A3 19951018; EP 0651643 A1 19950510; EP 0651643 A4 19951004; FI 946189 A0 19941230; FI 946189 A 19941230; GB 9213835 D0 19920812; HU T69409 A 19950928; IL 106158 A0 19931020; JP H08500821 A 19960130; KR 950702118 A 19950619; MA 22927 A1 19940401; MX 9303970 A 19940429; NO 945074 D0 19941229; NO 945074 L 19950216; OA 10122 A 19961218; RU 94046378 A 19961010; SI 9300350 A 19931231; SK 159994 A3 19960110; ZA 934645 B 19940125
DOCDB simple family (application)
US 9306238 W 19930630; AP 9300542 A 19930630; AU 4545993 A 19930630; BG 9931394 A 19941229; BR 9306748 A 19930630; CA 2138956 A 19930630; CN 93109540 A 19930630; CZ 334694 A 19930630; EP 93915499 A 19930630; FI 946189 A 19941230; GB 9213835 A 19920630; HU 9403833 A 19930630; IL 10615893 A 19930628; JP 50266094 A 19930630; KR 19940704802 A 19941229; MA 23217 A 19930628; MX 9303970 A 19930630; NO 945074 A 19941229; OA 60599 A 19941229; RU 94046378 A 19941229; SI 9300350 A 19930630; SK 159994 A 19930630; ZA 934645 A 19930626