EP 0651650 A4 19960417 - METHOD OF TREATING OPHTHALMIC DISORDERS USING TGF--g(b).
Title (en)
METHOD OF TREATING OPHTHALMIC DISORDERS USING TGF--g(b).
Title (de)
METHODE ZUR BEHANDLUNG VON AUGENKRANKHEITEN MITTELS TGF--g(b).
Title (fr)
PROCEDE POUR TRAITER DES AFFECTIONS OPHTALMIQUES A L'AIDE DU FACTEUR TRANSFORMANT DE CROISSANCE--g(b).
Publication
Application
Priority
- US 9306420 W 19930708
- US 91083492 A 19920708
- US 877893 A 19930122
Abstract (en)
[origin: WO9401124A1] This invention is a method for the treatment of ophthalmic disorders. The method is suitable for treatment of a variety of disorders including macular holes, macular degeneration, and retinal detachment and tears, cataracts, and corneal and scleral injuries. The method entails application of an effective amount of Transforming Growth Factor-(beta) (TGF-(beta)) to the affected region.
IPC 1-7
IPC 8 full level
A61K 38/22 (2006.01); A61K 38/18 (2006.01); A61P 27/02 (2006.01)
CPC (source: EP)
A61K 38/1841 (2013.01); A61P 27/02 (2017.12)
Citation (search report)
- [A] WO 9202247 A1 19920220 - CHIRON OPHTHALMICS INC [US]
- [X] JAMPEL H D ET AL: "TRANSFORMING GROWTH FACTOR -BETA IN HUMAN AQUEOUS HUMOR.", CURR EYE RES 9 (10). 1990. 963-970.
- [X] TRIPATHI R C ET AL: "Role of Growth Factors in the Uveal Tract of the Eye as Targeted to the Development of Nw Drugs", DRUG DEV RES 23(1). 1991. 1-25.
- [A] CONNOR T.B. ET AL.: "Correlation of Fibrosis and Transforming Growth Factor-beta Type 2 Levels in the Eye", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 85, no. 5, pages 1661 - 1666, XP002047092, DOI: doi:10.1172/JCI114065
- See references of WO 9401124A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9401124 A1 19940120; AU 4668193 A 19940131; CA 2138644 A1 19940120; EP 0651650 A1 19950510; EP 0651650 A4 19960417; JP H08502033 A 19960305
DOCDB simple family (application)
US 9306420 W 19930708; AU 4668193 A 19930708; CA 2138644 A 19930708; EP 93917021 A 19930708; JP 50350293 A 19930708