EP 0651744 A1 19950510 - 4-(4-FLUOROPHENYLMETHYL)-PIPERIDINES HAVING SIGMA AND D2-RECEPTOR AFFINITY.
Title (en)
4-(4-FLUOROPHENYLMETHYL)-PIPERIDINES HAVING SIGMA AND D2-RECEPTOR AFFINITY.
Title (de)
4-(4-FLUOROPHENYLMETHYL)-PIPERIDINE MIT EINER AFFINITÄT FÜR SIGMA UND D2-REZEPTOREN.
Title (fr)
4-(4-FLUOROPHENYLMETHYL)-PIPERIDINES PRESENTANT UNE AFFINITE AVEC LES RECEPTEURS SIGMA ET D2.
Publication
Application
Priority
- EP 9401594 W 19940517
- ES 9301062 A 19930518
Abstract (en)
[origin: WO9426712A1] The present invention relates to 1,4-disubstituted piperidine derivatives of general formula (I) wherein X is hydroxymethylene or methoxymethylene, Y is a 3-membered methylene sequence and R is a p-fluorophenyl group, as well as their pharmaceutically acceptable addition salts. These compounds are useful for treating sigma receptor-related nervous system diseases.
IPC 1-7
IPC 8 full level
A61K 31/445 (2006.01); A61K 31/451 (2006.01); A61P 25/00 (2006.01); C07D 211/22 (2006.01)
CPC (source: EP KR)
A61K 31/445 (2013.01 - KR); A61P 25/00 (2017.12 - EP); C07D 211/22 (2013.01 - EP KR)
Citation (search report)
See references of WO 9426712A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9426712 A1 19941124; AU 675332 B2 19970130; AU 6928494 A 19941212; CA 2140260 A1 19941124; EP 0651744 A1 19950510; ES 2066721 A1 19950301; ES 2066721 B1 19960216; FI 950197 A0 19950117; FI 950197 A 19950117; JP H07509255 A 19951012; KR 950702535 A 19950729; NO 301638 B1 19971124; NO 950062 D0 19950106; NO 950062 L 19950106; NZ 267100 A 19960925; TW 252975 B 19950801; ZA 943036 B 19950502
DOCDB simple family (application)
EP 9401594 W 19940517; AU 6928494 A 19940517; CA 2140260 A 19940517; EP 94917641 A 19940517; ES 9301062 A 19930518; FI 950197 A 19950117; JP 52499094 A 19940517; KR 19950700196 A 19950118; NO 950062 A 19950106; NZ 26710094 A 19940517; TW 83103579 A 19940422; ZA 943036 A 19940503