EP 0654043 A1 19950524 - METHOD FOR PREPARING A METAL-RADIONUCLIDE-LABELLED PROTEIN.
Title (en)
METHOD FOR PREPARING A METAL-RADIONUCLIDE-LABELLED PROTEIN.
Title (de)
HERSTELLUNGSMETHODE EINES METALLRADIONUKLID MARKIERTEN PROTEINS.
Title (fr)
PROCEDE POUR PREPARER UNE PROTEINE MARQUEE PAR UN RADIONUCLEIDE DE METAL.
Publication
Application
Priority
- EP 94915454 A 19940502
- EP 93201249 A 19930503
- US 9405022 W 19940502
Abstract (en)
[origin: WO9425488A1] The invention relates to a method of preparing a metal-radionuclide-labelled protein or proteinaceous material, which is intended for diagnostic or therapeutic application, by reacting a protein or a proteinaceous material with a bifunctional agent for coupling the radionuclide to the protein or proteinaceous material, a protein conjugate being formed by reaction between bifunctional agent and free amino groups or mercapto groups in the protein or proteinaceous material, and then complexing the radionuclide with the conjugate thus formed to a radionuclide complex. The invention further relates to the labelled protein or proteinaceous material thus obtained, and to a kit for preparing a radiopharmaceutical composition, which kit comprises the above-mentioned polyfunctional agent or a protein conjugate formed by reaction of a protein or proteinaceous material with said polyfunctional agent.
IPC 1-7
IPC 8 full level
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 51/00 (2006.01); A61K 51/08 (2006.01)
CPC (source: EP)
A61K 51/08 (2013.01); A61K 51/081 (2013.01); A61K 51/088 (2013.01); A61K 2121/00 (2013.01); A61K 2123/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE
DOCDB simple family (publication)
WO 9425488 A1 19941110; AU 6670894 A 19941121; CA 2141739 A1 19941110; EP 0654043 A1 19950524; EP 0654043 A4 19970716; MX PA94003278 A 20050401
DOCDB simple family (application)
US 9405022 W 19940502; AU 6670894 A 19940502; CA 2141739 A 19940502; EP 94915454 A 19940502; MX 9403278 A 19940503