EP 0655066 A1 19950531 - PROTEIN KINASE INHIBITORS AND RELATED COMPOUNDS COMBINED WITH TAXOL.
Title (en)
PROTEIN KINASE INHIBITORS AND RELATED COMPOUNDS COMBINED WITH TAXOL.
Title (de)
PROTEINKINASE-INHIBITOREN UND VERWANDTE VERBINDUNGEN KOMBINIERT MIT TAXOL.
Title (fr)
INHIBITEURS DE PROTEINE KINASE ET COMPOSES APPARENTES COMBINES AVEC DU TAXOL.
Publication
Application
Priority
- US 9307054 W 19930730
- US 92919992 A 19920812
Abstract (en)
[origin: WO9404541A2] This invention describes both known and novel compounds, some of which are protein kinase inhibitors, that may be combined with taxol type compounds. The combination of disclosed compounds plus taxol type compounds exhibits powerful synergistic effects and the combinations are useful in the treatment of cancer. The novel compounds and their synthesis are described. A compound of formula (I), above, is described wherein R1-R8 represent various substituents.
IPC 1-7
IPC 8 full level
A61K 31/40 (2006.01); A61P 35/00 (2006.01); C07D 498/22 (2006.01); C07H 9/06 (2006.01); C07H 19/23 (2006.01)
CPC (source: EP KR)
A61P 35/00 (2017.12 - EP); C07D 498/22 (2013.01 - EP KR); C07H 9/06 (2013.01 - EP); C07H 19/23 (2013.01 - EP)
Citation (search report)
See references of WO 9404541A2
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9404541 A2 19940303; WO 9404541 A3 19940609; AU 4787693 A 19940315; CA 2140653 A1 19940303; EP 0655066 A1 19950531; JP H08500112 A 19960109; KR 950702994 A 19950823
DOCDB simple family (application)
US 9307054 W 19930730; AU 4787693 A 19930730; CA 2140653 A 19930730; EP 93918422 A 19930730; JP 50628394 A 19930730; KR 19950700489 A 19950210