EP 0660710 A1 19950705 - COMPOSITIONS OF N-(PHOSPHONOACETYL)-L-ASPARTIC ACID AND METHODS OF THEIR USE AS BROAD SPECTRUM ANTIVIRALS.
Title (en)
COMPOSITIONS OF N-(PHOSPHONOACETYL)-L-ASPARTIC ACID AND METHODS OF THEIR USE AS BROAD SPECTRUM ANTIVIRALS.
Title (de)
ZUSAMMENSETZUNGEN VON N-(PHOSPHONOACETYL)-L-ASPARAGINSÄURE UND VERFAHREN FÜR IHRE VERWENDUNG ALS ANTIVIRALE MITTEL MIT BREITEM WIRKUNGSSPEKTRUM.
Title (fr)
COMPOSITIONS D'ACIDE N-(PHOSPHONOACETYLE)-L-ASPARTIQUE (PALA) ET PROCEDES D'UTILISATION DE CES DERNIERES EN TANT QUE COMPOSITIONS ANTIVIRALES A LARGE SPECTRE.
Publication
Application
Priority
- US 9302432 W 19930318
- US 85345492 A 19920318
- US 3223493 A 19930317
Abstract (en)
[origin: WO9318763A1] Compositions and methods are disclosed which utilize the broad spectrum antiviral activity of PALA. This compound and its pharmaceutically acceptable analogs possess potent activity while displaying minimal toxicity and, therefore, are characterized by a relatively high therapeutic index. Compositions optionally containing other therapeutic agents, such as other antiviral agents, are also disclosed and are found to possess synergistic and/or additive antiviral activity.
IPC 1-7
IPC 8 full level
A61K 31/195 (2006.01); A61K 31/66 (2006.01); A61K 31/70 (2006.01); A61K 38/21 (2006.01); A61K 45/06 (2006.01); A61P 31/12 (2006.01)
IPC 8 main group level
CPC (source: EP)
A61K 31/195 (2013.01); A61K 31/66 (2013.01); A61K 31/70 (2013.01); A61K 31/7004 (2013.01); A61K 38/212 (2013.01); A61K 45/06 (2013.01); A61P 31/12 (2017.12); Y02A 50/30 (2017.12)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9318763 A1 19930930; AU 3965993 A 19931021; BR 9306123 A 19970826; CA 2109435 A1 19930919; CA 2109435 C 19970311; CN 1080853 A 19940119; EP 0660710 A1 19950705; EP 0660710 A4 19950302; IL 105090 A0 19940826; IL 105090 A 19980816; IS 3987 A 19930919; JP H07507770 A 19950831; MX 9301527 A 19940228
DOCDB simple family (application)
US 9302432 W 19930318; AU 3965993 A 19930318; BR 9306123 A 19930318; CA 2109435 A 19930318; CN 93104593 A 19930318; EP 93909132 A 19930318; IL 10509093 A 19930317; IS 3987 A 19930318; JP 51670093 A 19930318; MX 9301527 A 19930318