EP 0665839 A1 19950809 - -i(ENANTIOMERIC CIS)-3-(4,6-DIHYDROXYCHROMAN-3-YLMETHYL)BENZOIC ACIDS.
Title (en)
-i(ENANTIOMERIC CIS)-3-(4,6-DIHYDROXYCHROMAN-3-YLMETHYL)BENZOIC ACIDS.
Title (de)
ENANTIOMERISCH CIS-3-(4,6-DIHYDROXYCHROMAN-3-YL-METHYL)-BENZOESÄUREN.
Title (fr)
ACIDES BENZOIQUES ENANTIOMERES -I(CIS)-3-(4,6-DIHYDROXYCHROMAN-3-YL-METHYLE).
Publication
Application
Priority
- US 9306061 W 19930630
- US 96433692 A 19921021
Abstract (en)
[origin: WO9408986A1] This invention relates to enantiomerically pure cis-3-(4,6-dihydroxychroman-3-ylmethyl)benzoic acids and processes for the preparation of such compounds. The compounds are intermediates useful in the preparation of optically pure enantiomers of cis-3-(6-arylmethyloxy-4-hydroxy-chroman-3-ylmethyl)aniline sulfonamides which are useful in the treatment of asthma, arthritis, psoriasis, ulcers, myocardial infarction and related diseases. More particularly it relates to (3R-cis)-3-(4,6-dihydroxychroman-3-ylmethyl)benzoic acid. It also relates to an improved process for the preparation of racemic cis-3-(4,6-dihydroxychroman-3-ylmethyl)benzoic acid.
IPC 1-7
IPC 8 full level
C07D 311/22 (2006.01)
CPC (source: EP KR)
C07D 311/22 (2013.01 - EP KR)
Citation (search report)
See references of WO 9408986A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9408986 A1 19940428; AU 4650493 A 19940509; CA 2146005 A1 19940428; CN 1090577 A 19940810; CZ 100895 A3 19951018; EP 0665839 A1 19950809; FI 934624 A0 19931020; FI 934624 A 19940422; HU 9302973 D0 19931228; HU T65128 A 19940428; IL 107293 A0 19940125; JP H07507811 A 19950831; KR 950704291 A 19951117; MX 9306526 A 19940429; MY 131378 A 20070830; NO 951507 D0 19950420; NO 951507 L 19950420; PL 308473 A1 19950807; ZA 937737 B 19950419
DOCDB simple family (application)
US 9306061 W 19930630; AU 4650493 A 19930630; CA 2146005 A 19930630; CN 93119050 A 19931020; CZ 100895 A 19930630; EP 93916752 A 19930630; FI 934624 A 19931020; HU 9302973 A 19931020; IL 10729393 A 19931014; JP 50996393 A 19930630; KR 19950701524 A 19950420; MX 9306526 A 19931020; MY PI9302174 A 19931020; NO 951507 A 19950420; PL 30847393 A 19930630; ZA 937737 A 19931019