EP 0666741 A1 19950816 - DITHIOCARBAMATES FOR THE TREATMENT OF ATHEROSCLEROSIS AND OTHER CARDIOVASCULAR AND INFLAMMATORY DISEASES.
Title (en)
DITHIOCARBAMATES FOR THE TREATMENT OF ATHEROSCLEROSIS AND OTHER CARDIOVASCULAR AND INFLAMMATORY DISEASES.
Title (de)
DITHIOCARBAMATE ZUR BEHANDLUNG VON ATHEROSKEROSIS UND WEITEREN KARDIOVASCULÄREN UND ENTZÜNDLICHEN ERKRANKUNGEN.
Title (fr)
DITHIOCARBAMATES DESTINES AU TRAITEMENT DE L'ATHEROSCLEROSE ET D'AUTRES MALADIES CARDIOVASCULAIRES ET INFLAMMATOIRES.
Publication
Application
Priority
- US 9310496 W 19931101
- US 96993492 A 19921030
Abstract (en)
[origin: WO9409772A1] Dithiocarboxylates, and in particular, dithiocarbamates, block the induced expression of the endothelial cell surface adhesion molecule VCAM-1, and are therefor useful in the treatment of cardiovascular disease, including atherosclerosis, post-angioplasty restenosis, coronary artery diseases, and angina, as well as noncardiovascular inflammatory diseases that are mediated by VCAM-1.
IPC 1-7
IPC 8 full level
C07D 295/10 (2006.01); A61K 31/145 (2006.01); A61K 31/185 (2006.01); A61K 31/198 (2006.01); A61K 31/27 (2006.01); A61K 31/325 (2006.01); A61K 31/40 (2006.01); A61K 31/445 (2006.01); A61K 45/06 (2006.01); A61P 9/00 (2006.01); A61P 9/02 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 29/00 (2006.01); C07C 333/04 (2006.01); C07C 333/06 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP US)
A61K 31/145 (2013.01 - EP US); A61K 31/185 (2013.01 - EP US); A61K 31/198 (2013.01 - EP US); A61K 31/325 (2013.01 - EP US); A61K 31/40 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 9/00 (2017.12 - EP); A61P 9/02 (2017.12 - EP); A61P 9/08 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 29/00 (2017.12 - EP); G01N 33/6872 (2013.01 - EP US); G01N 2333/70503 (2013.01 - EP US); G01N 2333/7056 (2013.01 - EP US); G01N 2800/323 (2013.01 - EP US)
Citation (search report)
See references of WO 9409772A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9409772 A1 19940511; AT E183089 T1 19990815; AU 5665394 A 19940524; AU 692426 B2 19980611; BG 62682 B1 20000531; BG 99604 A 19960228; BR 9307337 A 19990525; CA 2147881 A1 19940511; CA 2147881 C 19990907; CZ 111595 A3 19980715; DE 69326014 D1 19990916; DE 69326014 T2 19991223; DK 0666741 T3 19991206; EP 0666741 A1 19950816; EP 0666741 B1 19990811; ES 2136186 T3 19991116; GR 3031368 T3 20000131; HU 9501229 D0 19950628; HU T73440 A 19960729; JP 3254486 B2 20020204; JP H08506798 A 19960723; NO 951616 D0 19950427; NO 951616 L 19950427; NZ 258683 A 19990830; PL 179113 B1 20000731; PL 308673 A1 19950821; SK 56095 A3 19960605; US 5380747 A 19950110; US 5877203 A 19990302
DOCDB simple family (application)
US 9310496 W 19931101; AT 94902201 T 19931101; AU 5665394 A 19931101; BG 9960495 A 19950428; BR 9307337 A 19931101; CA 2147881 A 19931101; CZ 111595 A 19931101; DE 69326014 T 19931101; DK 94902201 T 19931101; EP 94902201 A 19931101; ES 94902201 T 19931101; GR 990402462 T 19990929; HU 9501229 A 19931101; JP 51138394 A 19931101; NO 951616 A 19950427; NZ 25868393 A 19931101; PL 30867393 A 19931101; SK 56095 A 19931101; US 72243896 A 19961017; US 96993492 A 19921030