EP 0667778 A4 19970416 - TREATMENT OF MELANOMA WITH ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE.
Title (en)
TREATMENT OF MELANOMA WITH ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE.
Title (de)
BEHANDLUNG VON MELANOMEN MIT ANTISENSE OLIGONUKLEOTIDEN GEGEN DAS C-MYB-PROTOONKOGEN.
Title (fr)
TRAITEMENT D'UN MELANOME AU MOYEN D'OLIGONUCLEOTIDES ANTI-CODANTS PAR RAPPORT AU PROTO-ONCOGENE C-MYB.
Publication
Application
Priority
- US 9209656 W 19921112
- US 79299991 A 19911115
Abstract (en)
[origin: WO9309789A1] Melanoma is treated by administering oligonucleotides having a nucleotide sequence complementary to at least a portion of the mRNA transcript of the human c-myb gene. These "antisense" oligonucleotides are hybridizable to the c-myb mRNA transcript.
IPC 1-7
IPC 8 full level
A61K 31/70 (2006.01); A61K 48/00 (2006.01); C07H 21/00 (2006.01); C07H 21/04 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 31/70 (2013.01); C07H 21/00 (2013.01); C12N 15/1135 (2013.01); A61K 38/00 (2013.01); C12N 2310/3125 (2013.01); C12N 2310/315 (2013.01)
Citation (search report)
- [YD] WO 9005445 A1 19900531 - UNIV TEMPLE [US]
- [Y] LINNENBACH, A. ET AL.: "Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 85, January 1988 (1988-01-01), WASHINGTON US, pages 74 - 78, XP002025496
- See references of WO 9309789A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9309789 A1 19930527; AU 3070992 A 19930615; CA 2123611 A1 19930527; EP 0667778 A1 19950823; EP 0667778 A4 19970416; JP H07501525 A 19950216
DOCDB simple family (application)
US 9209656 W 19921112; AU 3070992 A 19921112; CA 2123611 A 19921112; EP 92924379 A 19921112; JP 50935793 A 19921112