EP 0667870 A4 19980401 - COMPOSITIONS AND METHODS FOR MODIFYING THE REGULATORY ACTIVITY OF TGF--g(b).
Title (en)
COMPOSITIONS AND METHODS FOR MODIFYING THE REGULATORY ACTIVITY OF TGF--g(b).
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR MODIFIZIERUNG DER REGULATORISCHEN AKTIVITÄT VON TGF-BETA.
Title (fr)
COMPOSITIONS ET PROCEDES PERMETTANT DE MODIFIER L'ACTIVITE REGULATRICE DU FACTEUR DE CROISSANCE TISSULAIRE--g(b) (TGF--g(b)).
Publication
Application
Priority
- US 9310307 W 19931026
- US 96895392 A 19921030
- US 96895492 A 19921030
Abstract (en)
[origin: WO9410187A1] This invention provides a novel purified TGF- beta binding glycoprotein, endoglin, and isolated nucleic acid molecules that encode amino acid sequences corresponding to the TGF- beta -binding glycoprotein. Also provided is soluble endoglin-derived polypeptide, and fragments thereof. A pharmaceutical composition which comprises the purified endoglin-derived polypeptide or produced recombinantly methods and a pharmaceutically acceptable carrier is further provided as well as methods of treating patients by administering to the patient the pharmaceutical compositions of this invention.
IPC 1-7
C07H 21/02; C07H 21/04; C07K 9/00; A61K 38/00; C12N 1/21; C12N 5/10; C12N 15/70; C12P 21/00
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61P 1/00 (2006.01); A61P 1/16 (2006.01); A61P 9/10 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07K 14/47 (2006.01); C07K 14/71 (2006.01); C07K 16/28 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 1/16 (2017.12); A61P 9/10 (2017.12); A61P 29/00 (2017.12); A61P 37/00 (2017.12); A61P 43/00 (2017.12); C07K 14/71 (2013.01); C07K 16/2863 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- No further relevant documents disclosed
- See references of WO 9410187A1
Designated contracting state (EPC)
AT BE CH DE DK FR GB IT LI NL SE
DOCDB simple family (publication)
WO 9410187 A1 19940511; AU 5541094 A 19940524; CA 2147754 A1 19940511; EP 0667870 A1 19950823; EP 0667870 A4 19980401; JP H08504577 A 19960521
DOCDB simple family (application)
US 9310307 W 19931026; AU 5541094 A 19931026; CA 2147754 A 19931026; EP 94900408 A 19931026; JP 51128594 A 19931026