EP 0667922 A1 19950823 - PROCESS FOR THE PREPARATION OF TAXANE DERIVATIVES, NOVEL TAXANES SO OBTAINED AND ANTITUMOUR AND ANTILEUKAEMIA COMPOSITIONS CONTAINING SAME.
Title (en)
PROCESS FOR THE PREPARATION OF TAXANE DERIVATIVES, NOVEL TAXANES SO OBTAINED AND ANTITUMOUR AND ANTILEUKAEMIA COMPOSITIONS CONTAINING SAME.
Title (de)
VERFAHREN ZUR HERSTELLUNG VON TAXANDERIVATE, NEUE DABEI ERHALTENE TAXANE UND DIESE ENTHALTENDE ANTITUMORAL UND ANTILEUKÄMISCH WIRKENDE ZUSAMMENSETZUNGEN.
Title (fr)
PROCEDE DE PREPARATION DE DERIVES DU TAXANE, NOUVEAUX TAXANES AINSI OBTENUS ET LES COMPOSITIONS ANTITUMORALES ET ANTILEUCEMIQUES QUI LES CONTIENNENT.
Publication
Application
Priority
- FR 9301102 W 19931110
- FR 9213586 A 19921112
Abstract (en)
[origin: FR2697841A1] Process for the electrochemical preparation of taxane derivatives of general formula (I), based on a taxane derivative of general formula (III). The invention also concerns pharmaceutical compositions with outstanding antitumour and antileukaemia properties which contain a novel product of general formula (I) wherein R3 is a radical of general formula (II). In general formulae (I) and (III), R is a hydrogen atom or an acetyl or alkoxyacetyl radical, one of the symbols R1 or R2 is a hydrogen atom and the other is a hydroxy radical, R3 is a hydrogen atom or a radical of general formula (II) wherein Ar is an aryl radical and R4 is a benzoyl radical or a R5-O-CO- radical in which R5 is an alkyl, alkenyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl radical.
IPC 1-7
IPC 8 full level
A61K 31/335 (2006.01); A61K 31/337 (2006.01); A61P 35/00 (2006.01); C07D 305/14 (2006.01); C25B 3/25 (2021.01)
CPC (source: EP KR)
A61K 31/335 (2013.01 - KR); A61K 31/337 (2013.01 - KR); A61P 35/00 (2017.12 - EP KR); C07D 305/14 (2013.01 - EP KR); C25B 3/25 (2021.01 - EP KR); C25B 9/23 (2021.01 - KR); C25B 11/046 (2021.01 - KR)
Citation (search report)
See references of WO 9411547A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
FR 2697841 A1 19940513; FR 2697841 B1 19950113; AU 5425794 A 19940608; CA 2149240 A1 19940526; CZ 122495 A3 19951213; EP 0667922 A1 19950823; FI 952294 A0 19950511; FI 952294 A 19950511; JP H08503261 A 19960409; KR 950704540 A 19951120; MX 9306883 A 19950131; NO 951772 D0 19950505; NO 951772 L 19950505; PL 308957 A1 19950904; RU 95112464 A 19970220; SK 60895 A3 19960306; WO 9411547 A1 19940526; ZA 938366 B 19940613
DOCDB simple family (application)
FR 9213586 A 19921112; AU 5425794 A 19931110; CA 2149240 A 19931110; CZ 122495 A 19931110; EP 93924688 A 19931110; FI 952294 A 19950511; FR 9301102 W 19931110; JP 51178694 A 19931110; KR 19950701883 A 19950511; MX 9306883 A 19931104; NO 951772 A 19950505; PL 30895793 A 19931110; RU 95112464 A 19950511; SK 60895 A 19931110; ZA 938366 A 19931109