EP 0669836 A1 19950906 - THERAPEUTIC APPLICATION OF CHIMERIC AND RADIOLABELED ANTIBODIES TO HUMAN B LYMPHOCYTE RESTRICTED DIFFERENTIATION ANTIGEN FOR TREATMENT OF B CELL LYMPHOMA.
Title (en)
THERAPEUTIC APPLICATION OF CHIMERIC AND RADIOLABELED ANTIBODIES TO HUMAN B LYMPHOCYTE RESTRICTED DIFFERENTIATION ANTIGEN FOR TREATMENT OF B CELL LYMPHOMA.
Title (de)
THERAPEUTISCHE VERWENDUNG VON CHIMERISCHEN UND MARKIERTEN ANTIKÖRPER GEGEN MENSCHLICHEN B LYMPHOZYT BESCHRÄNKTER DIFFERENZIERUNG ANTIGEN FÜR DIE BEHANDLUNG VON B-ZELL-LYMPHOMA.
Title (fr)
APPLICATION THERAPEUTIQUE D'ANTICORPS CHIMERIQUES ET RADIO-MARQUES CONTRE L'ANTIGENE A DIFFERENTIATION RESTREINTE DES LYMPHOCYTES B HUMAINS POUR LE TRAITEMENT DU LYMPHOME DES CELLULES B.
Publication
Application
Priority
- US 9310953 W 19931112
- US 97889192 A 19921113
- US 14909993 A 19931103
Abstract (en)
[origin: EP1005870A2] Disclosed herein is an immunologically active, chimeric anti-CD20 antibody for use as a medicament, which antibody is capable of substantial B-cell depletion when administered to a subject.
IPC 1-7
IPC 8 full level
C12N 15/02 (2006.01); A61K 31/375 (2006.01); A61K 31/573 (2006.01); A61K 31/664 (2006.01); A61K 31/704 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 47/48 (2006.01); A61K 51/00 (2006.01); A61K 51/08 (2006.01); A61K 51/10 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); C12N 1/21 (2006.01); C12N 5/02 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); A61K 38/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP US)
A61K 47/6849 (2017.08 - EP US); A61K 51/1027 (2013.01 - EP US); A61K 51/1093 (2013.01 - EP US); A61P 35/00 (2018.01 - EP); C07K 16/2887 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); A61K 2039/505 (2013.01 - EP US); C07K 2317/24 (2013.01 - EP US); C07K 2317/56 (2013.01 - EP US); C07K 2317/732 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US); C12N 2799/028 (2013.01 - EP US); Y10S 424/80 (2013.01 - EP US); Y10S 424/801 (2013.01 - EP US); Y10S 530/808 (2013.01 - EP US); Y10S 530/809 (2013.01 - EP US); Y10S 530/867 (2013.01 - EP US)
Citation (examination)
- JOURNAL OF IMMUNOLOGY vol. 139, no. 10 , 15 November 1987 , BALTIMORE US pages 3521 - 3526 ALVIN Y. LIU ET AL. 'PRODUCTION OF A MOUSE-HUMAN CHIMERIC
- MONOCLONAL ANTIBODY TO CD20 WITH POTENT FC-DEPENDENT BIOLOGIC ACTIVITY.' cited in the application
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
US 5776456 A 19980707; AT E139900 T1 19960715; AT E196606 T1 20001015; AU 5603294 A 19940608; AU 688743 B2 19980319; BG 62386 B1 19991029; BG 99701 A 19960228; CA 2149329 A1 19940526; CA 2149329 C 20080715; DE 122004000036 I1 20050707; DE 69303494 D1 19960808; DE 69303494 T2 19970116; DE 69329503 D1 20001102; DE 69329503 T2 20010503; DK 0669836 T3 19961014; DK 0752248 T3 20001113; EP 0669836 A1 19950906; EP 0669836 B1 19960703; EP 0752248 A1 19970108; EP 0752248 B1 20000927; EP 1005870 A2 20000607; EP 1005870 A3 20021023; EP 1005870 B1 20090121; ES 2091684 T3 19961101; ES 2152483 T3 20010201; FI 112033 B 20031031; FI 952327 A0 19950512; FI 952327 A 19950710; GR 3020731 T3 19961130; GR 3035119 T3 20010330; JP 2001010974 A 20010116; JP 2006262907 A 20061005; JP 3095175 B2 20001003; JP 4091235 B2 20080528; JP 4203080 B2 20081224; JP H08503468 A 19960416; LU 91089 I2 20040916; LV 11732 A 19970420; LV 11732 B 19971020; MD 1367 B2 19991231; MD 1367 C2 20001130; NL 300156 I1 20040901; NL 300156 I2 20041001; NO 2006011 I1 20061002; NO 2006011 I2 20110221; NO 20061094 L 19950713; NO 20061095 L 19950713; NO 321137 B1 20060327; NO 326271 B1 20081027; NO 329146 B1 20100830; NO 951903 D0 19950512; NO 951903 L 19950713; NZ 258392 A 19970922; PL 174494 B1 19980831; PL 174721 B1 19980930; PL 309002 A1 19950918; PT 752248 E 20010131; RO 118524 B1 20030630; RU 2139731 C1 19991020; US 2002197255 A1 20021226; US 2003021781 A1 20030130; US 2003095963 A1 20030522; US 2005186205 A1 20050825; US 2008089893 A9 20080417; US 5843439 A 19981201; US 6399061 B1 20020604; US 6682734 B1 20040127; US 7381560 B2 20080603; US 7422739 B2 20080909; WO 9411026 A2 19940526; WO 9411026 A3 19940818
DOCDB simple family (application)
US 47627595 A 19950607; AT 94901444 T 19931112; AT 96200772 T 19931112; AU 5603294 A 19931112; BG 9970195 A 19950605; CA 2149329 A 19931112; DE 122004000036 C 19931112; DE 69303494 T 19931112; DE 69329503 T 19931112; DK 94901444 T 19931112; DK 96200772 T 19931112; EP 94901444 A 19931112; EP 96200772 A 19931112; EP 99123967 A 19931112; ES 94901444 T 19931112; ES 96200772 T 19931112; FI 952327 A 19950512; GR 20000402807 T 20001219; GR 960402096 T 19960807; JP 2000126317 A 20000421; JP 2006135870 A 20060515; JP 51237694 A 19931112; LU 91089 C 20040716; LV 960373 A 19960917; MD 950311 A 19931112; NL 300156 C 20040716; NO 2006011 C 20060918; NO 20061094 A 20060307; NO 20061095 A 20060307; NO 951903 A 19950512; NZ 25839293 A 19931112; PL 30900293 A 19931112; PL 32065893 A 19931112; PT 96200772 T 19931112; RO 9500888 A 19931112; RU 95112506 A 19931112; US 47581395 A 19950607; US 47581595 A 19950607; US 47896795 A 19950607; US 90592801 A 20010717; US 91169201 A 20010725; US 91170301 A 20010725; US 9310953 W 19931112; US 95603904 A 20041004