EP 0671950 A1 19950920 - IMMUNOLOGICAL PURGING OF TUMOR CELLS FROM BONE MARROW USING MICROSPHERES AND MONOCLONAL ANTIBODIES.
Title (en)
IMMUNOLOGICAL PURGING OF TUMOR CELLS FROM BONE MARROW USING MICROSPHERES AND MONOCLONAL ANTIBODIES.
Title (de)
IMMUNOLOGISCHE REINIGUNG VON TUMORZELLEN AUS DEM KNOCHENMARK MITTELS MIKROSPHÄREN UND MONOKLONALEN ANTIKÖRPERN.
Title (fr)
PURGE IMMUNOLOGIQUE DE CELLULES TUMORALES DE LA MOELLE OSSEUSE A L'AIDE DE MICROSPHERES ET D'ANTICORPS MONOCLONAUX.
Publication
Application
Priority
- US 9309891 W 19931018
- US 96310492 A 19921019
Abstract (en)
[origin: WO9408621A1] A method is described for the immunological purging of tumor cells from the bone marrow of a patient having B cell lymphoma. The purged bone marrow may be used for therapeutic autologous bone marrow transplantation. Microspheres and a plurality of anti-B cell monoclonal antibodies are used to remove tumor cells from bone marrow, without removal or lysis of non-tumor cells, to a level not detectable by polymerase chain reaction assay.
IPC 1-7
IPC 8 full level
G01N 33/577 (2006.01); A61K 9/50 (2006.01); A61K 39/395 (2006.01); A61K 39/44 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12P 21/08 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 35/02 (2017.12); C07K 16/3061 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9408621 A1 19940428; AU 5361694 A 19940509; AU 681605 B2 19970904; CA 2147010 A1 19940428; EP 0671950 A1 19950920; EP 0671950 A4 19960731; JP H08502489 A 19960319
DOCDB simple family (application)
US 9309891 W 19931018; AU 5361694 A 19931018; CA 2147010 A 19931018; EP 93923903 A 19931018; JP 51030494 A 19931018