Global Patent Index - EP 0672153 A4

EP 0672153 A4 19970507 - VECTOR TO DELIVER AND EXPRESS FOREIGN GENE.

Title (en)

VECTOR TO DELIVER AND EXPRESS FOREIGN GENE.

Title (de)

VEKTOR FÜR DIE VERABREICHUNG UND EXPRESSION FREMDER GENE.

Title (fr)

VECTEUR TRANSPORTANT ET EXPRIMANT UN GENE ETRANGER.

Publication

EP 0672153 A4 19970507 (EN)

Application

EP 93921748 A 19930928

Priority

  • AU 9300495 W 19930928
  • AU PL497492 A 19920928

Abstract (en)

[origin: WO9408022A1] A vector for delivering a foreign gene to a target cell for expression of the foreign gene is provided. The vector comprises a (-) sense RNA genome contained within a ribonucleoprotein complex within a virus-like particle constituted from structural proteins of a (-) sense RNA virus. The (-) sense RNA genome includes one or more foreign genes but does not include genes for replication of the (-) sense RNA virus. Methods of preparing the vector are disclosed, as well as pharmaceutical compositions containing the vector, and methods of delivering the expression product of the foreign gene to a target cell.

IPC 1-7

C12N 15/64; C12N 15/86; A61K 48/00

IPC 8 full level

A61K 31/70 (2006.01); A61K 48/00 (2006.01); A61P 31/12 (2006.01); C07H 21/04 (2006.01); C07K 14/145 (2006.01); C12N 7/04 (2006.01); C12N 15/09 (2006.01); C12N 15/86 (2006.01); C12N 15/866 (2006.01); C12N 15/87 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61P 31/12 (2017.12); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01); C12N 2710/14143 (2013.01); C12N 2760/20122 (2013.01); C12N 2760/20123 (2013.01)

Citation (search report)

  • [Y] EP 0440219 A1 19910807 - SCHWEIZ SERUM & IMPFINST [CH]
  • [PYD] WO 9301833 A1 19930204 - COMMW SCIENT IND RES ORG [AU]
  • [DY] K.H. PARK ET AL.: "Rescue of a foreign gene by Sendai virus", PROC. NATL.ACAD SCI., vol. 88, July 1991 (1991-07-01), NATL. ACAD SCI.,WASHINGTON,DC,US;, pages 5537 - 5541, XP002025853
  • [Y] THOMSEN D R ET AL: "EXPRESSION OF FELINE LEUKAEMIA VIRUS GP85 AND GAG PROTEINS AND ASSEMBLY INTO VIRUS-LIKE PARTICLES USING THE BACULOVIRUS EXPRESSION VECTOR SYSTEM", JOURNAL OF GENERAL VIROLOGY, vol. 73, no. PART 07, 1 July 1992 (1992-07-01), pages 1819 - 1824, XP000288658
  • [DY] P.L. COLLINS ET AL.: "Rescue of synthetic analogs of respiratory syncytial virus genomic RNA and effect of truncations and mutations on the expression of a foreign reporter gene", PROC. NATL.ACAD SCI., vol. 88, November 1991 (1991-11-01), NATL. ACAD SCI.,WASHINGTON,DC,US;, pages 9663 - 9667, XP002025854
  • [DA] M. SCHUBERT ET AL.: "Insertion of the human immunodeficiency virus CD4 receptor into the envelope of vesicular stomatitis virus particles", J. VIROLOGY, vol. 66, no. 3, March 1992 (1992-03-01), AM.SOC.MICROBIOL.,WASHINGTON,US, pages 1579 - 1589, XP000644669
  • See references of WO 9408022A1

Designated contracting state (EPC)

CH DE FR GB LI

DOCDB simple family (publication)

WO 9408022 A1 19940414; EP 0672153 A1 19950920; EP 0672153 A4 19970507; IL 107139 A0 19931228; JP H08501453 A 19960220; ZA 937164 B 19940523

DOCDB simple family (application)

AU 9300495 W 19930928; EP 93921748 A 19930928; IL 10713993 A 19930928; JP 50851894 A 19930928; ZA 937164 A 19930927