EP 0673433 A1 19950927 - HEPATIC MODEL.
Title (en)
HEPATIC MODEL.
Title (de)
LEBERMODELL.
Title (fr)
MODELE HEPATIQUE.
Publication
Application
Priority
- US 9310874 W 19931112
- US 98196492 A 19921125
Abstract (en)
[origin: WO9412662A1] A method for screening a chemical compound for hepatotoxicity or choleostatic potential, hepatic extraction potential, hepatic discharge into the bile, metabolite production, or the ability to alter hepatic cell metabolism, using a primary hepatic cell culture with a functional bile canalicular network, is disclosed.
IPC 1-7
C12Q 1/18; C12Q 1/02; C12N 5/06; C12N 5/02; C12N 5/00; C12N 1/00
IPC 8 full level
C12N 5/06 (2006.01); C12N 5/071 (2010.01); C12Q 1/02 (2006.01); C12Q 1/18 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP)
C12N 5/0671 (2013.01); G01N 33/5008 (2013.01); C12N 2503/04 (2013.01); C12N 2533/54 (2013.01); G01N 2500/00 (2013.01)
Citation (search report)
See references of WO 9412662A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9412662 A1 19940609; AU 5552794 A 19940622; CA 2154701 A1 19940609; EP 0673433 A1 19950927; JP H08503610 A 19960423
DOCDB simple family (application)
US 9310874 W 19931112; AU 5552794 A 19931112; CA 2154701 A 19931112; EP 94900612 A 19931112; JP 51317994 A 19931112