EP 0676959 A4 19960103 - ENDOTHELIN RECEPTOR ANTAGONISTS.
Title (en)
ENDOTHELIN RECEPTOR ANTAGONISTS.
Title (de)
ENDOTHELINREZEPTORANTAGONISTEN.
Title (fr)
ANTAGONISTES DES RECEPTEURS DE L'ENDOTHELINE.
Publication
Application
Priority
- US 9312435 W 19931221
- US 99546692 A 19921222
Abstract (en)
[origin: WO9414434A1] Indole derivatives of formula (1) wherein the substituents are defined herein are disclosed. The compounds are useful in methods of antagonizing endothelin receptors, treating hypertension, treating renal failure and treating cerebrovascular disease. Pharmaceutical compositions are also disclosed.
IPC 1-7
A61K 31/40; A61K 31/405; C07D 209/12; C07D 209/22; C07D 405/10; C07D 405/14
IPC 8 full level
A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61P 9/00 (2006.01); A61P 9/12 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); A61P 43/00 (2006.01); C07D 209/30 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 9/12 (2017.12); A61P 13/02 (2017.12); A61P 15/00 (2017.12); A61P 43/00 (2017.12); C07D 405/04 (2013.01); C07D 405/06 (2013.01)
Citation (search report)
- [X] EP 0449196 A2 19911002 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
- [A] EP 0460679 A2 19911211 - BANYU PHARMA CO LTD [JP]
- See references of WO 9414434A1
Designated contracting state (EPC)
BE CH DE FR GB IT LI NL
DOCDB simple family (publication)
WO 9414434 A1 19940707; AU 5873594 A 19940719; CN 1096513 A 19941221; EP 0676959 A1 19951018; EP 0676959 A4 19960103; JP H08504826 A 19960528; MX 9400071 A 19940729; ZA 939516 B 19940606
DOCDB simple family (application)
US 9312435 W 19931221; AU 5873594 A 19931221; CN 93119929 A 19931222; EP 94904877 A 19931221; JP 51538694 A 19931221; MX 9400071 A 19940103; ZA 939516 A 19931220