EP 0677052 A1 19951018 - NOVEL QUINOLONE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME.
Title (en)
NOVEL QUINOLONE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME.
Title (de)
NEUE CHINOLON-DERIVATE UND VERFAHREN ZU DEREN HERSTELLUNG.
Title (fr)
NOUVEAUX DERIVES DE LA QUINOLONE ET PROCEDES POUR LEUR PREPARATION.
Publication
Application
Priority
- KR 9300122 W 19931229
- KR 920026039 A 19921229
- KR 930027072 A 19931209
Abstract (en)
[origin: WO9414813A1] The present invention relates to novel quinolone compounds of formula (I), optical isomers and pharmaceutically acceptable salts thereof. In formula (I), A represents nitrogen or (a), in which Y represents hydrogen, halogen, lower alkyl or lower alkoxy or together with R1 forms -CH2CH2CH2-, -CH2CH2CH(CH3)-, -OCH2CH2-, -OCH2CH(CH3)-, -SCH2CH2- or -SCH2CH(CH3)-; R1 is as defined above or represents a straight chain or cyclic lower alkyl group having 1 to 3 carbon atoms or a straight chain or cyclic lower alkyl group having 1 to 3 carbon atoms which is substituted with a halogen atom, a phenyl group or a phenyl group substituted with one or two halogen atoms; R2 and R3 may be the same or different and represent independently hydrogen, nitro, methoxycarbonyl and ethoxycarbonyl; R4 represents hydrogen, lower alkyl, lower alkoxy or an amino-protecting group; R5, R6, R7 and R8 may be the same or different and represent independently hydrogen, lower alkyl optionally substituted by amino, hydroxyl or halogen; X represents hydrogen, halogen, amino or lower alkyl; and optical isomers and pharmaceutically acceptable salts thereof.
IPC 1-7
C07D 487/18; C07D 519/00; C07D 471/04; A61K 31/47; A61K 31/435; A61K 31/44
IPC 8 full level
C07D 471/04 (2006.01); C07D 519/00 (2006.01)
CPC (source: EP KR)
C07D 471/04 (2013.01 - EP KR); Y02P 20/55 (2015.11 - EP)
Citation (search report)
See references of WO 9414813A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9414813 A1 19940707; AU 5718094 A 19940719; CN 1092069 A 19940914; EP 0677052 A1 19951018; KR 940014395 A 19940718; MX 9400002 A 19940729
DOCDB simple family (application)
KR 9300122 W 19931229; AU 5718094 A 19931229; CN 93121482 A 19931229; EP 94903115 A 19931229; KR 930027072 A 19931209; MX 9400002 A 19940103