EP 0678029 A1 19951025 - METHOD FOR USING POLYNUCLEOTIDES, OLIGONUCLEOTIDES AND DERIVATIVES THEREOF TO TREAT VARIOUS DISEASE STATES.
Title (en)
METHOD FOR USING POLYNUCLEOTIDES, OLIGONUCLEOTIDES AND DERIVATIVES THEREOF TO TREAT VARIOUS DISEASE STATES.
Title (de)
VERFAHREN ZUM GEBRAUCH VON POLY-, OLIGONUKLEOTIDEN UND DEREN DERIVATE FÜR DIE BEHANDELUNG VON VERSCHIEDENEN KRANKHEITSSTADIEN.
Title (fr)
PROCEDE D'UTILISATION DE POLYNUCLEOTIDES, D'OLIGONUCLEOTIDES ET DE LEURS DERIVES POUR TRAITER DIVERS ETATS PATHOLOGIQUES.
Publication
Application
Priority
- US 9400638 W 19940113
- US 239593 A 19930113
Abstract (en)
[origin: WO9415621A1] Oligodeoxyribonucleotides, polydeoxyribonucleotides and derivatives thereof, such as defibrotide, are agents of genetic modulation at the levels of transcription, translation, secondary messengers and cellular signal transduction systems. Various disease states can be treated by modifying the dose of such agents in response to observed fluctuations (e.g., increase, decrease, appearance, disappearance) in normal, disease and repair markers.
IPC 1-7
IPC 8 full level
C12N 15/11 (2006.01); C12N 15/117 (2010.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 31/70 (2013.01); C12N 15/117 (2013.01); A61K 38/00 (2013.01); C12N 2310/18 (2013.01)
Citation (search report)
See references of WO 9415621A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9415621 A1 19940721; AU 6090494 A 19940815; AU 692433 B2 19980611; CA 2153778 A1 19940721; CA 2153778 C 20040706; EP 0678029 A1 19951025
DOCDB simple family (application)
US 9400638 W 19940113; AU 6090494 A 19940113; CA 2153778 A 19940113; EP 94907246 A 19940113