Global Patent Index - EP 0681478 A4

EP 0681478 A4 20000906 - VACCINES AGAINST DISEASES CAUSED BY ENTEROPATHOGENIC ORGANISMS USING ANTIGENS ENCAPSULATED WITHIN BIODEGRADABLE-BIOCOMPATIBLE MICROSPHERES

Title (en)

VACCINES AGAINST DISEASES CAUSED BY ENTEROPATHOGENIC ORGANISMS USING ANTIGENS ENCAPSULATED WITHIN BIODEGRADABLE-BIOCOMPATIBLE MICROSPHERES

Title (de)

IMPFSTOFFE GEGEN KRANKHEITEN HERVORGERUFEN DURCH ENTEROPATHOGENE ORGANISMEN UNTER VERWENDUNG VON ANTIGENEN, DIE IN BIOLOGISCH ABBAUBARE UND BIOLOGISCH-VERTRÄGLICHE MIKROSPHÄREN EINGEKAPSELT SIND

Title (fr)

VACCINS CONTRE DES MALADIES CAUSEES PAR DES ORGANISMES ENTEROPATHOGENES UTILISANT DES ANTIGENES ENCAPSULES DANS DES MICROSPHERES BIODEGRADABLES ET BIOCOMPATIBLES

Publication

EP 0681478 A4 20000906 (EN)

Application

EP 94911515 A 19940309

Priority

  • US 9402536 W 19940309
  • US 3494993 A 19930322

Abstract (en)

[origin: WO9421289A1] This invention is directed to oral parenteral and intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.

IPC 1-7

A61K 39/02; A61K 9/26; A61K 39/29; A61K 39/108; A61K 9/52

IPC 8 full level

A61K 9/16 (2006.01); A61K 39/02 (2006.01); A61K 39/108 (2006.01); A61K 39/29 (2006.01)

CPC (source: EP)

A61K 9/1647 (2013.01); A61K 39/0258 (2013.01); A61K 39/12 (2013.01); A61K 39/292 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55555 (2013.01); C12N 2730/10134 (2013.01); Y02A 50/30 (2017.12)

Citation (search report)

  • [X] WO 9219263 A1 19921112 - US ARMY [US]
  • [XY] REID R H ET AL: "Preclinical evaluation of microencapsulated CFA/II oral vaccine against enterotoxigenic Escherichia coli.", INTERNATIONAL CONFERENCE ON VACCINES FOR ENTERIC DISEASES;CAMBRIDGE, ENGLAND, UK; APRIL 13-15, 1992, vol. 11, no. 2, 1993, Vaccine 1993, pages 159 - 167, XP000886976, ISSN: 0264-410X
  • [X] EDELMAN ROBERT ET AL: "Immunization of rabbits with enterotoxigenic Escherichia coli colonization factor antigen (CFA/I) encapsulated in biodegradable microspheres of poly (lactide-co-glycolide).", INTERNATIONAL CONFERENCE ON VACCINES FOR ENTERIC DISEASES;CAMBRIDGE, ENGLAND, UK; APRIL 13-15, 1992, vol. 11, no. 2, 1993, Vaccine 1993, pages 155 - 158, XP000886975, ISSN: 0264-410X
  • [Y] BOYLAN M ET AL: "NUCLEOTIDE SEQUENCE OF THE GENE ENCODING THE MAJOR SUBUNIT OF CS3 FIMBRIAE OF ENTEROTOXIGENIC ESCHERICHIA-COLI", INFECTION AND IMMUNITY 1988, vol. 56, no. 12, 1988, pages 3297 - 3300, XP000909617, ISSN: 0019-9567
  • [PX] REID R ET AL: "Colonization factor antigen/II (CFA/II) incorporated into biodegradable, biocompatible microspheres as an intestinal vaccine against enterotoxigenic Escherichia coli: A safety, immunization, and efficacy human study.", JOINT MEETING OF THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS AND THE CLINICAL IMMUNOLOGY SOCIETY;DENVER, COLORADO, USA; MAY 21-25, 1993, vol. 150, no. 8 PART 2, 1993, Journal of Immunology 1993, pages 323A, XP000909651, ISSN: 0022-1767
  • [A] NELLORE R ET AL: "APPLICATION OF BIODEGRADABLE MICROSPHERES TO HEPATITIS B SURFACE ANTIGEN VACCINATION SYSTEM", PHARMACEUTICAL RESEARCH (NEW YORK) 1991, vol. 8, no. 10 SUPPL., 1991, pages S151, XP002026578, ISSN: 0724-8741
  • [A] LEVINE M M ET AL: "COLI SURFACE ANTIGENS 1 AND 3 OF COLONIZATION FACTOR ANTIGEN II POSITIVE ENTERO TOXIGENIC ESCHERICHIA-COLI MORPHOLOGY PURIFICATION AND IMMUNE RESPONSES IN HUMANS", INFECTION AND IMMUNITY 1984, vol. 44, no. 2, 1984, pages 409 - 420, XP000886967, ISSN: 0019-9567
  • See references of WO 9421289A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9421289 A1 19940929; AU 6400194 A 19941011; EP 0681478 A1 19951115; EP 0681478 A4 20000906

DOCDB simple family (application)

US 9402536 W 19940309; AU 6400194 A 19940309; EP 94911515 A 19940309