EP 0682513 A1 19951122 - SMALL DIAMETER NANOCAPSULES, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF.
Title (en)
SMALL DIAMETER NANOCAPSULES, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF.
Title (de)
NANOKAPSELN MIT KLEINEM DURCHMESSER, VERFAHREN FÜR IHRE HERSTELLUNG UND IHRE ANWENDUNGEN.
Title (fr)
NANOCAPSULES DE FAIBLE DIAMETRE, LEUR PROCEDE DE PREPARATION ET LEURS APPLICATIONS.
Publication
Application
Priority
- IE 9400001 W 19940110
- RU 93001196 A 19930111
Abstract (en)
[origin: WO9415590A1] Nanocapsules typically having a diameter in the range of 20-150 nm are provided and consist of a polymeric shell formed of a surface active poly(alkyl cyanoacrylate) material arranged in one or more layers. The polymeric shell can be composed of a surface active poly(alkyl 2-cyanoacrylate) having general formula (I), wherein R is -CH2-(-CH2-)-mCH3, -CH2-(-CH2-)-mCOOH, -CH2-(-CH2-)-mCOOR', or -CH2CH2-O-(-CH2CH2-O-)-mR'; R' is -CH3, -CH2-(-CH2-)-mCH3, -C-(-CH3-)-2-CH2-C(CH3)3, or -O-Ar; m has a value of from 0 to 20; and n has a value of from 1 to 20, formed by the interfacial polymerisation of self-arranged micelles of the cyanoacrylate monomers. The nanocapsules can be used to encapsulate a wide range of water soluble and water insoluble active agents in high yield for delivery to a target system or locus, for example, drugs for use in therapy or prophylaxis.
IPC 1-7
IPC 8 full level
CPC (source: EP)
A61K 9/5138 (2013.01); A61K 9/5146 (2013.01); A61K 9/5161 (2013.01)
Citation (search report)
See references of WO 9415590A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9415590 A1 19940721; AU 5714194 A 19940815; CA 2153343 A1 19940721; EP 0682513 A1 19951122; PL 310072 A1 19951127
DOCDB simple family (application)
IE 9400001 W 19940110; AU 5714194 A 19940110; CA 2153343 A 19940110; EP 94902998 A 19940110; PL 31007294 A 19940110