Global Patent Index - EP 0683790 B1

EP 0683790 B1 20000426 - AUTOMATED SYNTHESIS OF OLIGONUCLEOTIDES

Title (en)

AUTOMATED SYNTHESIS OF OLIGONUCLEOTIDES

Title (de)

AUTOMATISIERTE SYNTHESE VON OLIGONUKLEOTIDEN

Title (fr)

SYNTHESE AUTOMATISEE D'OLIGONUCLEOTIDES

Publication

EP 0683790 B1 20000426 (EN)

Application

EP 94907420 A 19940204

Priority

  • US 9401271 W 19940204
  • US 1673993 A 19930211

Abstract (en)

[origin: WO9418226A1] Apparatus and method for the automated synthesis of DNA segments utilizing multiple reaction columns (11), all of which are open at the inlet end (13) to the atmosphere of a reaction chamber (10). A moveable reagent supply line outlet (12) is positioned adjacent to the column inlet end (13) to apply reagent to each of the columns (11) according to an input sequence of delivery. The delivery sequence is under processor control. Reagents are removed from all columns (11) simultaneously through the application of vacuum (22) at the outlet end (14) of each column (11). The device enables the parallel synthesis of large numbers of different oligonucleotide sequences of different lengths.

IPC 1-7

C07K 1/04; C07K 17/00; C12M 1/36; G05D 7/00; B01J 19/00

IPC 8 full level

C12M 1/00 (2006.01); B01J 19/00 (2006.01); C07K 1/04 (2006.01); C12M 1/36 (2006.01); C40B 40/06 (2006.01); C40B 60/14 (2006.01)

CPC (source: EP US)

B01J 19/0046 (2013.01 - EP US); B01J 2219/00286 (2013.01 - EP US); B01J 2219/00308 (2013.01 - EP US); B01J 2219/00364 (2013.01 - EP US); B01J 2219/00416 (2013.01 - EP US); B01J 2219/00418 (2013.01 - EP US); B01J 2219/00423 (2013.01 - EP US); B01J 2219/005 (2013.01 - EP US); B01J 2219/00585 (2013.01 - EP US); B01J 2219/0059 (2013.01 - EP US); B01J 2219/00596 (2013.01 - EP US); B01J 2219/00689 (2013.01 - EP US); B01J 2219/00695 (2013.01 - EP US); B01J 2219/00722 (2013.01 - EP US); C40B 40/06 (2013.01 - EP US); C40B 60/14 (2013.01 - EP US)

Designated contracting state (EPC)

BE DE FR GB NL

DOCDB simple family (publication)

WO 9418226 A1 19940818; DE 69424151 D1 20000531; DE 69424151 T2 20000921; EP 0683790 A1 19951129; EP 0683790 A4 19960313; EP 0683790 B1 20000426; JP H08506813 A 19960723; US 5368823 A 19941129; US 5541314 A 19960730

DOCDB simple family (application)

US 9401271 W 19940204; DE 69424151 T 19940204; EP 94907420 A 19940204; JP 51823694 A 19940204; US 1673993 A 19930211; US 29110994 A 19940802